4I6F: Selective & Brain-Permeable Polo-like Kinase-2 (Plk-2) Inhibitors that Reduce -Synuclein Phosphorylation in Rat Brain

PDB ID: 4I6FDownload
MMDB ID: 115281
PDB Deposition Date: 2012/11/29
Updated in MMDB: 2013/11
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 4I6F: monomeric; determined by author and by software (PISA)
Molecular Components in 4I6F
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Plk2
(Gene symbol: PLK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(7R)-8-cyclopentyl-7-ethyl-5-methyl-2-(2-phenyl-1H-imidazol-1-yl)-7,8-dihydropteridin-6(5H)-one(7R)-8-cyclopentyl-7-ethyl-5-methyl-2-(2-phenyl-1H-imidazol-1-yl)-7,8-dihydropteridin-6(5H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303