3KW4: Crystal structure of cytochrome 2B4 in complex with the anti-platelet drug ticlopidine

PDB ID: 3KW4Download
MMDB ID: 84801
PDB Deposition Date: 2009/11/30
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.67  Å
Source Organism:
Similar Structures:
Biological Unit for 3KW4: monomeric; determined by author and by software (PISA)
Molecular Components in 3KW4
Label Count Molecule
Protein (1 molecule)
1
Cytochrome P450 2B4
(Gene symbol: CYP2B4)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
1
ticlopidineticlopidine
3
2
5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE
4
1
2-{[(3alpha,5alpha,7alpha,8alpha,10alpha,12alpha,17alpha)-3,12-bis{2-[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]ethoxy}cholan-7-yl]oxy}ethyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside2-{[(3alpha,5alpha,7alpha,8alpha,10alpha,12alpha,17alpha)-3,12-bis{2-[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]ethoxy}cholan-7-yl]oxy}ethyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303