4KSP: Crystal Structure of Human B-raf bound to a DFG-out Inhibitor TAK-632

PDB ID: 4KSPDownload
MMDB ID: 112088
PDB Deposition Date: 2013/5/17
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.93  Å
Source Organism:
Similar Structures:
Biological Unit for 4KSP: dimeric; determined by author
Molecular Components in 4KSP
Label Count Molecule
Proteins (2 molecules)
2
Serine/threonine-protein Kinase B-raf
(Gene symbol: BRAF)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamideN-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303