Abstract
Three new Lycopodium alkaloids, carinatumins A-C (1-3), have been isolated from the club moss Lycopodium carinatum. Structures and stereochemistry of 1-3 were elucidated on the basis of 2D NMR correlations. Carinatumins A (1) and B (2) exhibited a potent inhibitory activity against acetylcholinesterase.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / chemistry
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Alkaloids / isolation & purification
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Carbenicillin / analogs & derivatives*
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Carbenicillin / isolation & purification
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Carbenicillin / pharmacology
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Cholinesterase Inhibitors / chemistry*
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Cholinesterase Inhibitors / isolation & purification*
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Lycopodium / chemistry*
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Plants, Medicinal / chemistry
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Pyridones / isolation & purification*
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Pyridones / pharmacology
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Stereoisomerism
Substances
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Alkaloids
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Cholinesterase Inhibitors
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Pyridones
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carinatumin B
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carinatumin C
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carbenicillin indanyl
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Carbenicillin