Novel tacrine-related drugs as potential candidates for the treatment of Alzheimer's disease

Alejandro Romero; Ramón Cacabelos; María J Oset-Gasque; Abdelouahid Samadi; José Marco-Contelles

doi:10.1016/j.bmcl.2013.02.017

Novel tacrine-related drugs as potential candidates for the treatment of Alzheimer's disease

Bioorg Med Chem Lett. 2013 Apr 1;23(7):1916-22. doi: 10.1016/j.bmcl.2013.02.017. Epub 2013 Feb 16.

Authors

Alejandro Romero¹, Ramón Cacabelos, María J Oset-Gasque, Abdelouahid Samadi, José Marco-Contelles

Affiliation

¹ Department of Toxicology and Pharmacology, Faculty of Veterinary Medicine, Complutense University of Madrid, 28040-Madrid, Spain.

PMID: 23481643
DOI: 10.1016/j.bmcl.2013.02.017

Abstract

A summary of the recently published efforts on tacrine derivatives as a renewed potential therapeutic approach for the treatment of Alzheimer's disease is presented.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Alzheimer Disease / drug therapy*
Animals
Humans
Molecular Structure
Tacrine / analogs & derivatives*
Tacrine / chemical synthesis
Tacrine / chemistry
Tacrine / therapeutic use*

Substances

Tacrine