Abstract
An Aeromonas allosaccharophila environmental isolate recovered from the Seine River (Paris, France) produced a novel extended-spectrum beta-lactamase, PER-6, that shared 92% amino acid identity with the closest ss-lactamase, PER-2. The kinetic properties of PER-6 showed a slightly increased affinity for carbapenems. The bla(PER-6) gene was chromosomally located and bracketed by non-transposon-related structures.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aeromonas / drug effects
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Aeromonas / enzymology*
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Aeromonas / genetics*
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Aeromonas / isolation & purification
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Animals
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Base Sequence
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DNA Primers / genetics
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DNA, Bacterial / genetics
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Genes, Bacterial
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Humans
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Kinetics
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Paris
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Water Microbiology
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beta-Lactamases / genetics*
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beta-Lactamases / metabolism*
Substances
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DNA Primers
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DNA, Bacterial
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beta-lactamase PER-2, Enterobacteriaceae
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beta-Lactamases