2. Cell Cycle/DNA Damage
  3. CDK
  4. CLK1/4-IN-1

CLK1/4-IN-1 (compound 31) is a potent and selective Clk1 and Clk4 inhibitor with an IC50 value of 9.7 nM and 6.6 nM, respectively. CLK1/4-IN-1 has growth inhibitory activities against T24 cancer cells with GI50 of 1.1 μM. CLK1/4-IN-1 can be used for researching anticancer.

For research use only. We do not sell to patients.

CLK1/4-IN-1 Chemical Structure

CLK1/4-IN-1 Chemical Structure

CAS No. : 3029431-90-8

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CLK1/4-IN-1 Related Antibodies

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Description

CLK1/4-IN-1 (compound 31) is a potent and selective Clk1 and Clk4 inhibitor with an IC50 value of 9.7 nM and 6.6 nM, respectively. CLK1/4-IN-1 has growth inhibitory activities against T24 cancer cells with GI50 of 1.1 μM. CLK1/4-IN-1 can be used for researching anticancer[1].

IC50 & Target[1]

CLK1

9.7 nM (IC50)

CLK4

6.6 nM (IC50)

Molecular Weight

375.83

Formula

C18H14ClNO4S
CAS No.
SMILES

O=C(NC(C1=C(C=CC(Cl)=C1)OC)=O)C2=CC3=CC(OC)=CC=C3S2
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Purity & Documentation
References
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CLK1/4-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CLK1/4-IN-13029431-90-8CDKCyclin dependent kinaseAnticancerT24 cellsAntiproliferationInhibitorinhibitorinhibit

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