Compile Data Set for Download or QSAR
maximum 50k data
Found 38 with Last Name = 'abet' and Initial = 'v'
TargetBeta-casein(Bos taurus (bovine))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: >1nMAssay Description:Binding affinity to bovine beta-casein A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: >1nMAssay Description:Binding affinity to induced myeloid leukemia cell differentiation protein 1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 10 [11-204](Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: >1nMAssay Description:Binding affinity to Bcl-b (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466393(CHEMBL4277499)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of recombinant His-tagged human Axl (473 to end residues) cytoplasmic domain expressed in insect system using poly (Glu-Ala-Tyr) peptide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50044472(CHEMBL3313966)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM27078(N-[3-(1H-1,3-benzodiazol-2-yl)-1H-pyrazol-4-yl]ben...)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466394(CHEMBL4285809)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant GST-tagged human Mer (578 to 872 residues) cytoplasmic domain expressed in Baculovirus system using poly (Glu-Ala-Tyr) pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466392(CHEMBL4285448)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant GST-tagged human Mer (578 to 872 residues) cytoplasmic domain expressed in Baculovirus system using poly (Glu-Ala-Tyr) pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutathione S-transferase Mu 1(Mus musculus)
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50044547(CHEMBL3314090)
Affinity DataIC50:  50nMAssay Description:Inhibition of mouse GSTM1-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM27078(N-[3-(1H-1,3-benzodiazol-2-yl)-1H-pyrazol-4-yl]ben...)
Affinity DataIC50:  52nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466392(CHEMBL4285448)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant His-tagged human Axl (473 to end residues) cytoplasmic domain expressed in insect system using poly (Glu-Ala-Tyr) peptide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM36511(5-((2-Carboxy-1H-benzo[g]indol-1-yl)methyl)isoxazo...)
Affinity DataIC50:  80nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466393(CHEMBL4277499)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant GST-tagged human Mer (578 to 872 residues) cytoplasmic domain expressed in Baculovirus system using poly (Glu-Ala-Tyr) pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM36510(1-(Carboxymethyl)-1H-benzo[g]indole-2-carboxylic a...)
Affinity DataIC50:  200nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466394(CHEMBL4285809)
Affinity DataIC50:  270nMAssay Description:Inhibition of recombinant GST-tagged human Tyro3 (451 to 890 residues) cytoplasmic domain expressed in Baculovirus expression system using poly (Glu-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466393(CHEMBL4277499)
Affinity DataIC50:  690nMAssay Description:Inhibition of recombinant GST-tagged human Tyro3 (451 to 890 residues) cytoplasmic domain expressed in Baculovirus expression system using poly (Glu-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM24637(2-(1H-pyrazol-3-yl)-1H-1,3-benzodiazole | JMC52379...)
Affinity DataIC50:  910nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50060582(1,10-Bis(trimethyl ammonium)decane dibromide | 1,1...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466394(CHEMBL4285809)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant His-tagged human Axl (473 to end residues) cytoplasmic domain expressed in insect system using poly (Glu-Ala-Tyr) peptide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466392(CHEMBL4285448)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of recombinant GST-tagged human Tyro3 (451 to 890 residues) cytoplasmic domain expressed in Baculovirus expression system using poly (Glu-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Ochsner Clinic

Curated by ChEMBL
LigandPNGBDBM50555693(CHEMBL4800229)
Affinity DataIC50:  4.82E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) in baculosomes preincubated for 20 mins followed by addition of CYP enzyme-specific substrate and NADP+ and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Ochsner Clinic

Curated by ChEMBL
LigandPNGBDBM50555693(CHEMBL4800229)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) in baculosomes preincubated for 20 mins followed by addition of CYP enzyme-specific substrate and NADP+ and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Ochsner Clinic

Curated by ChEMBL
LigandPNGBDBM50555692(CHEMBL4800549)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) in baculosomes preincubated for 20 mins followed by addition of CYP enzyme-specific substrate and NADP+ and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Ochsner Clinic

Curated by ChEMBL
LigandPNGBDBM26197(CHEMBL112 | N-(4-hydroxyphenyl)acetamide | Norco |...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) in baculosomes preincubated for 20 mins followed by addition of CYP enzyme-specific substrate and NADP+ and mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Ochsner Clinic

Curated by ChEMBL
LigandPNGBDBM26197(CHEMBL112 | N-(4-hydroxyphenyl)acetamide | Norco |...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) in baculosomes preincubated for 20 mins followed by addition of CYP enzyme-specific substrate and NADP+ and mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 3A4(Homo sapiens (Human))
Ochsner Clinic

Curated by ChEMBL
LigandPNGBDBM50555692(CHEMBL4800549)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) in baculosomes preincubated for 20 mins followed by addition of CYP enzyme-specific substrate and NADP+ and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM24637(2-(1H-pyrazol-3-yl)-1H-1,3-benzodiazole | JMC52379...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466391(CHEMBL4293688)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant His-tagged human Axl (473 to end residues) cytoplasmic domain expressed in insect system using poly (Glu-Ala-Tyr) peptide a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466391(CHEMBL4293688)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human Tyro3 (451 to 890 residues) cytoplasmic domain expressed in Baculovirus expression system using poly (Glu-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Psl Research University

Curated by ChEMBL
LigandPNGBDBM50466391(CHEMBL4293688)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human Mer (578 to 872 residues) cytoplasmic domain expressed in Baculovirus system using poly (Glu-Ala-Tyr) pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM36501(2-(5-chloro-3-methylbenzo[b]thiophen-2-yl)acetic a...)
Affinity DataIC50: >5.00E+8nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM36500(2-(5-Chlorobenzo[b]thiophen-3-yl)acetic acid, 1 | ...)
Affinity DataIC50: >5.00E+8nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM36503((S)-1-((Benzyloxy)carbonyl)indoline-2-carboxylic a...)
Affinity DataIC50: >5.00E+8nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM36502(2-(6-Methoxybenzofuran-3-yl)acetic acid, 3 | CID73...)
Affinity DataIC50: >5.00E+8nMAssay Description:Inhibition of FPPS (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50044549(CHEMBL3314093)
Affinity DataKd:  0nMAssay Description:Binding affinity to acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50044548(CHEMBL3314092)
Affinity DataKd:  0nMAssay Description:Binding affinity to acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50149201(3,8-DIAMINO-6-PHENYL-5-[6-[1-[2-[(1,2,3,4-TETRAHYD...)
Affinity DataKd:  0nMAssay Description:Binding affinity to acetylcholine esterase (unknown origin)More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Institut De Chimie Des Substances Naturelles

Curated by ChEMBL
LigandPNGBDBM50044550(CHEMBL3314097)
Affinity DataKd:  200nMAssay Description:Inhibition of Akt1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed