Compile Data Set for Download or QSAR
maximum 50k data
Found 9 with Last Name = 'abraham' and Initial = 'n'
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50590141(CHEMBL5176133)
Affinity DataIC50:  23nMAssay Description:Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as inhibition of choline induced intracellular calcium by FLI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of bovine lens aldose reductase with DL-glyceraldehyde as substrateMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50590140(CHEMBL5202162)
Affinity DataIC50:  176nMAssay Description:Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as inhibition of choline induced intracellular calcium by FLI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of bovine lens aldose reductase with DL-glyceraldehyde as substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM16415((1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetic...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of bovine lens aldose reductase with DL-glyceraldehyde as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine-binding protein(Lymnaea stagnalis)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50590141(CHEMBL5176133)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [3H]-epibatidine from recombinant Lymnaea stagnalis Acetylcholine-binding protein by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholine-binding protein(Lymnaea stagnalis)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50590140(CHEMBL5202162)
Affinity DataIC50:  2.00E+4nMAssay Description:Displacement of [3H]-epibatidine from recombinant Lymnaea stagnalis Acetylcholine-binding protein by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50590143(CHEMBL5180704)
Affinity DataIC50:  3.50E+4nMAssay Description:Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as inhibition of choline induced intracellular calcium by FLI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50590142(CHEMBL5170487)
Affinity DataIC50:  4.60E+4nMAssay Description:Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as inhibition of choline induced intracellular calcium by FLI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed