Compile Data Set for Download or QSAR
maximum 50k data
Found 114 with Last Name = 'abrams' and Initial = 'j'
LigandPNGBDBM15067((2S)-1-(1H-indol-3-yl)-3-(5-isoquinolin-6-ylpyridi...)
Affinity DataIC50:  1.30nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.5nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050935((S)-2-{(S)-4-Methyl-2-[(S)-4-methylsulfanyl-2-(3-p...)
Affinity DataIC50:  2nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050933((S)-2-((S)-2-{(S)-2-[3-(4-Chloro-phenyl)-ureido]-4...)
Affinity DataIC50:  2nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050929(2-((S)-2-{(S)-2-[3-(4-Methoxy-phenyl)-ureido]-4-me...)
Affinity DataIC50:  2nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Abbott Laboratories

LigandPNGBDBM15067((2S)-1-(1H-indol-3-yl)-3-(5-isoquinolin-6-ylpyridi...)
Affinity DataIC50:  2.10nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Abbott Laboratories

LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  3.60nMpH: 7.4 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  6.5nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  6.60nMpH: 7.4 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15067((2S)-1-(1H-indol-3-yl)-3-(5-isoquinolin-6-ylpyridi...)
Affinity DataIC50:  6.80nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15022(3-[(2S)-2-amino-3-({5-[(E)-2-(pyridin-4-yl)ethenyl...)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050937((S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-b...)
Affinity DataIC50:  20nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050945((S)-2-[(R)-2-((S)-2-{(R)-2-[(S)-2-(3-Adamantan-1-y...)
Affinity DataIC50:  20nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050928((S)-2-[(R)-4-Methyl-2-((S)-2-{(R)-4-methyl-2-[(S)-...)
Affinity DataIC50:  20nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15068(13b (R-) | 6-{5-[(2R)-2-amino-3-(1H-indol-3-yl)pro...)
Affinity DataIC50:  26nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050946((S)-2-{(S)-4-Methyl-2-[(S)-4-methylsulfanyl-2-(3-p...)
Affinity DataIC50:  30nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15067((2S)-1-(1H-indol-3-yl)-3-(5-isoquinolin-6-ylpyridi...)
Affinity DataIC50:  35nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
Abbott Laboratories

LigandPNGBDBM15022(3-[(2S)-2-amino-3-({5-[(E)-2-(pyridin-4-yl)ethenyl...)
Affinity DataIC50:  38nMpH: 7.4 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM4851((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataIC50:  42nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050942((S)-2-[(R)-4-Methyl-2-((S)-2-{(R)-4-methyl-2-[(S)-...)
Affinity DataIC50:  50nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)
Affinity DataIC50:  68nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050939((S)-2-{(S)-4-Methyl-2-[(S)-4-methylsulfanyl-2-(3-m...)
Affinity DataIC50:  100nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050926((S)-2-((R)-4-Methyl-2-{(S)-2-[(R)-4-methyl-2-((S)-...)
Affinity DataIC50:  100nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15066(5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-(pyrid...)
Affinity DataIC50:  190nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050928((S)-2-[(R)-4-Methyl-2-((S)-2-{(R)-4-methyl-2-[(S)-...)
Affinity DataIC50:  200nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050943((S)-2-[(R)-2-((S)-2-{(R)-2-[(S)-2-(3-Isopropyl-ure...)
Affinity DataIC50:  200nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15023(3-[(2S)-2-amino-3-({5-[2-(pyridin-4-yl)ethynyl]pyr...)
Affinity DataIC50:  210nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15064(N-[(2S)-2-amino-3-(1H-indol-3-yl)propyl]-5-(isoqui...)
Affinity DataIC50:  210nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)
Affinity DataIC50:  220nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15050(N-(4-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyr...)
Affinity DataIC50:  227nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15022(3-[(2S)-2-amino-3-({5-[(E)-2-(pyridin-4-yl)ethenyl...)
Affinity DataIC50:  257nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15037(3-[(2S)-2-amino-3-{[5-(pyridin-4-yl)pyridin-3-yl]o...)
Affinity DataIC50:  260nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15067((2S)-1-(1H-indol-3-yl)-3-(5-isoquinolin-6-ylpyridi...)
Affinity DataIC50:  270nMAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15065(3-N-[(2S)-2-amino-3-(1H-indol-3-yl)propyl]-5-N-(is...)
Affinity DataIC50:  270nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM15062(3-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-6-(pyrid...)
Affinity DataIC50:  300nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050931((S)-2-[(R)-2-((S)-2-{(R)-2-[(S)-2-(3-Butyl-ureido)...)
Affinity DataIC50:  300nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050927((S)-2-{(S)-2-[(S)-2-(3-Isopropenyl-ureido)-4-methy...)
Affinity DataIC50:  300nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050945((S)-2-[(R)-2-((S)-2-{(R)-2-[(S)-2-(3-Adamantan-1-y...)
Affinity DataIC50:  300nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050934((S)-2-{(S)-2-[(S)-2-(3-Butyl-ureido)-4-methylsulfa...)
Affinity DataIC50:  300nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15022(3-[(2S)-2-amino-3-({5-[(E)-2-(pyridin-4-yl)ethenyl...)
Affinity DataIC50:  354nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM4851((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataIC50:  490nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050943((S)-2-[(R)-2-((S)-2-{(R)-2-[(S)-2-(3-Isopropyl-ure...)
Affinity DataIC50:  500nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050942((S)-2-[(R)-4-Methyl-2-((S)-2-{(R)-4-methyl-2-[(S)-...)
Affinity DataIC50:  500nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  570nMpH: 7.4 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050931((S)-2-[(R)-2-((S)-2-{(R)-2-[(S)-2-(3-Butyl-ureido)...)
Affinity DataIC50:  600nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050940((S)-2-{(S)-2-[(S)-2-(3-Benzyl-ureido)-4-methylsulf...)
Affinity DataIC50:  600nMAssay Description:Antagonistic activity was determined by measuring the ability to inhibit superoxide production(stimulated by fMLF) using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15021(3-[(2S)-2-amino-3-phenylpropoxy]-5-[(E)-2-(pyridin...)
Affinity DataIC50:  690nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050940((S)-2-{(S)-2-[(S)-2-(3-Benzyl-ureido)-4-methylsulf...)
Affinity DataIC50:  800nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Johnson Matthey Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50050926((S)-2-((R)-4-Methyl-2-{(S)-2-[(R)-4-methyl-2-((S)-...)
Affinity DataIC50:  800nMAssay Description:Binding affinity towards fMLF receptor using human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 114 total ) | Next | Last >>
Jump to: