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Found 109 with Last Name = 'adang' and Initial = 'ae'
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118719(7-Amino-3-{[1-(2-amino-3-cyclohexyl-propionyl)-pyr...)
Affinity DataKi:  0.140nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118730(7-Amino-3-(2-{[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  0.210nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118728(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  0.290nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118739(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  0.290nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118732(1-(2-Amino-3-phenyl-propionyl)-pyrrolidine-2-carbo...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118729(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  0.330nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118731((2-{2-[5-Amino-1-(oxazole-2-carbonyl)-pentylcarbam...)
Affinity DataKi:  0.420nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118735(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  0.5nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118738(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  0.820nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118718(CHEMBL343804 | {2-[2-(5-Amino-1-phenethylaminooxal...)
Affinity DataKi:  0.840nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118723(CHEMBL342672 | CYCLOTHEONAMIDE A | N-[14-Benzyl-18...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118727(2-((R)-1-((S)-2-(((S)-7-amino-1-isopropoxy-1,2-dio...)
Affinity DataKi:  1.10nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118720(7-Amino-3-{[1-(2-amino-3-phenyl-propionyl)-pyrroli...)
Affinity DataKi:  1.40nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118717((S)-N-((S)-6-amino-1-oxo-1-(thiazol-2-yl)hexan-2-y...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118737((2-{2-[5-Amino-1-(thiazole-2-carbonyl)-pentylcarba...)
Affinity DataKi:  2.60nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118721((S)-N-((S)-6-amino-1-oxo-1-(thiazol-2-yl)hexan-2-y...)
Affinity DataKi:  3.5nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118722(2-Amino-N-{[5-amino-1-(thiazole-2-carbonyl)-pentyl...)
Affinity DataKi:  13nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118725(7-Amino-3-{[1-(3-carboxy-2-phenylmethanesulfonylam...)
Affinity DataKi:  15nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50073316(CHEMBL114715 | INOGATRAN | {(R)-1-Cyclohexylmethyl...)
Affinity DataKi:  15nMAssay Description:The inhibitory activity of the compound was tested against thrombin (IIa)More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataKi:  19nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118734(6-Amino-2-[2-(5-{[1-(2-amino-3-phenyl-propionyl)-p...)
Affinity DataKi:  28nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118724((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  146nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118716((S)-1-(3,3-diphenyl-propionyl)-pyrrolidine-2-carbo...)
Affinity DataKi:  204nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118715(7-Amino-3-({1-[2-(carboxymethyl-amino)-3-cyclohexy...)
Affinity DataKi:  376nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Nv Organon Scientific Development Group

Curated by ChEMBL
LigandPNGBDBM50073316(CHEMBL114715 | INOGATRAN | {(R)-1-Cyclohexylmethyl...)
Affinity DataKi:  675nMAssay Description:The inhibitory activity of the compound was tested against trypsinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118733(1-(3,3-Diphenyl-propionyl)-pyrrolidine-2-carboxyli...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118714(7-Methoxy-naphthalene-2-sulfonic acid [5-amino-1-(...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118736(7-Methoxy-naphthalene-2-sulfonic acid [5-amino-1-(...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50118726(CHEMBL334701 | N-[5-Amino-1-(thiazole-2-carbonyl)-...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory activity against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076948((R)-1-((3R,4R,4aR)-Decahydro-isoquinoline-1-carbon...)
Affinity DataIC50:  48nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50073322(((R)-2-Cyclohexyl-1-{cyclopentyl-[(3-guanidino-pro...)
Affinity DataIC50:  110nMAssay Description:Inhibition of thrombin (IIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076945((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076949((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Affinity DataIC50:  160nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076952(3-{[(S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50073311(((R)-2-Cyclohexyl-1-{cyclopentyl-[(3-guanidino-3-o...)
Affinity DataIC50:  240nMAssay Description:Inhibition of thrombin (IIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50073320(((R)-2-Cyclohexyl-1-{cyclopentyl-[(3-guanidino-3-o...)
Affinity DataIC50:  240nMAssay Description:Inhibition of thrombin (IIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076953((R)-1-(3,3-Diphenyl-propionyl)-pyrrolidine-2-carbo...)
Affinity DataIC50:  260nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076951(((R)-2-Cyclohexyl-1-{methyl-[(2-oxo-1-piperidin-4-...)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataIC50:  550nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076946((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Affinity DataIC50:  590nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076954(((R)-2-Cyclohexyl-1-{[(2-oxo-1-piperidin-4-ylmethy...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50073323(CHEMBL121608 | {(R)-1-Cyclohexylmethyl-2-[(S)-2-(3...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of thrombin (IIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50073316(CHEMBL114715 | INOGATRAN | {(R)-1-Cyclohexylmethyl...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of thrombin (IIa)More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076947((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50073313(CHEMBL421057 | N-(3-Guanidino-3-oxo-propyl)-2-(6-m...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of thrombin (IIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076945((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076948((R)-1-((3R,4R,4aR)-Decahydro-isoquinoline-1-carbon...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076950(CHEMBL284008 | {(R)-2-Cyclohexyl-1-[(S)-1-(2-oxo-1...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory activity against thrombin with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Research And Development

Curated by ChEMBL
LigandPNGBDBM50076946((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibitory activity against Coagulation factor X with respect to ArgatrobanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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