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Found 22 with Last Name = 'afza' and Initial = 'n'
TargetCathepsin B(Homo sapiens (Human))
The City University Of New York

Curated by ChEMBL
LigandPNGBDBM50213272(CHEBI:6426 | Leupeptin)
Affinity DataKi:  5nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The City University Of New York

Curated by ChEMBL
LigandPNGBDBM50491873(CHEMBL2387617)
Affinity DataKi:  8.60E+4nMAssay Description:Inhibition of human liver cathepsin B using Z-RR-para-nitroanilide as substrate assessed as reversible equilibrium binding constant by Kitz-Wilson pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86082(Tetraketone, 19)
Affinity DataIC50:  7.80E+3nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86085(Tetraketone, 22)
Affinity DataIC50:  1.25E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86070(Tetraketone, 3)
Affinity DataIC50:  1.63E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86077(Tetraketone, 11)
Affinity DataIC50:  1.75E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86074(Tetraketone, 8)
Affinity DataIC50:  2.13E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Karachi

LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)
Affinity DataIC50:  2.26E+4nMpH: 8.0 T: 2°CAssay Description:A mixture of test compound (10 μL; 1 mM) in MeOH, type-1B lipoxygenase (EC 1.13.11.12; from soyabean) (20 μL; 70 units) in 0.1 M aqueous ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86072(Tetraketone, 6)
Affinity DataIC50:  2.64E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86080(Tetraketone, 15)
Affinity DataIC50:  2.71E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86078(Tetraketone, 12)
Affinity DataIC50:  2.84E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86076(Tetraketone, 10)
Affinity DataIC50:  3.08E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86069(Tetraketone, 2)
Affinity DataIC50:  3.30E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86075(Tetraketone, 9)
Affinity DataIC50:  3.31E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86083(Tetraketone, 20)
Affinity DataIC50:  3.54E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86084(Tetraketone, 21)
Affinity DataIC50:  5.15E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86079(Tetraketone, 14)
Affinity DataIC50:  5.29E+4nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Karachi

LigandPNGBDBM233017(Conferin (1))
Affinity DataIC50:  5.52E+4nMpH: 8.0 T: 2°CAssay Description:A mixture of test compound (10 μL; 1 mM) in MeOH, type-1B lipoxygenase (EC 1.13.11.12; from soyabean) (20 μL; 70 units) in 0.1 M aqueous ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSeed linoleate 13S-lipoxygenase-1(Glycine max (soybean))
University Of Karachi

LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  1.00E+5nMpH: 8.0 T: 2°CAssay Description:A mixture of test compound (10 μL; 1 mM) in MeOH, type-1B lipoxygenase (EC 1.13.11.12; from soyabean) (20 μL; 70 units) in 0.1 M aqueous ph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86081(Tetraketone, 16)
Affinity DataIC50:  1.91E+5nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86073(Tetraketone, 7)
Affinity DataIC50:  1.96E+5nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 12-lipoxygenase, 12R-type(Homo sapiens (Human))
Pharmaceutical Research Centre

LigandPNGBDBM86071(Tetraketone, 4)
Affinity DataIC50:  1.98E+5nMpH: 8.0 T: 2°CAssay Description:In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed