Compile Data Set for Download or QSAR
maximum 50k data
Found 247 with Last Name = 'agans-fantuzzi' and Initial = 'j'
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261110(CHEMBL493982 | Ethyl [(3aR,4aR,8aR,9aS)-9(S)-[(E)-...)
Affinity DataKi:  1.10nMAssay Description:Antagonist activity at human PAR1 in HCASMC assessed as inhibition of thrombin-induced calcium effluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50260518(CHEMBL442649 | ethyl (1R,3aR,4aR,6R,8aR,9S,9aS)-9-...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50173419((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-{(E)-2-[5-(3-tr...)
Affinity DataKi:  2.70nMAssay Description:Inhibitory constant aganist Protease-activated receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261116(CHEMBL453277 | ethyl methyl((1R,3aR,4aR,6R,8aR,9S,...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261114(CHEMBL500551 | Ethyl [(1R,3aR,4aR,6R,8aR,9S,9aS)-9...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50222015((1R,3aR,4aS,8aS,9S,9aS)-decahydro-1-methyl-3-oxo-9...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261061(CHEMBL493633 | N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E...)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261062(1-ethyl-3-((1R,3aR,4aR,6R,8aR,9S,9aS)-9-((E)-2-(5-...)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50260520(CHEMBL458264 | ethyl (1R,3aR,4aR,6R,8aR,9S,9aS)-9-...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261117(CHEMBL446344 | ethyl (1R,3aR,4aR,6R,8aR,9S,9aS)-9-...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261111(CHEMBL493983 | methyl (1R,3aR,4aR,6R,8aR,9S,9aS)-9...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261060(CHEMBL493632 | N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261017(CHEMBL493792 | N-((1R,3aR,4aR,6R,8aR,9S,9aS)-9-((E...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261018(CHEMBL494618 | N-((1R,3aR,4aR,6R,8aR,9S,9aS)-9-((E...)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261110(CHEMBL493982 | Ethyl [(3aR,4aR,8aR,9aS)-9(S)-[(E)-...)
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261108(CHEMBL447996 | N-((1R,3aR,4aR,6R,8aR,9S,9aS)-1-met...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50260519(CHEMBL521531 | ethyl (1R,3aR,4aR,6R,8aR,9S,9aS)-9-...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261107(CHEMBL493975 | N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50202073((3R,3aS,4S,4aR,7R,8aR,9aR)-decahydro-7-hydroxy-3-m...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50260521(CHEMBL507697 | ethyl (1R,3aR,4aR,6R,8aR,9S,9aS)-9-...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50260516(CHEMBL495422 | ethyl (1R,3aR,4aR,6R,8aR,9S,9aS)-9-...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50173417((3R,3aS,4S,4aR,8aS,9aR)-4-(2-(6-ethylpyridin-2-yl)...)
Affinity DataKi:  12nMAssay Description:Inhibitory constant aganist Protease-activated receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261109(CHEMBL449425 | ethyl (1R,3aR,4aR,6R,8aR,9S,9aS)-1-...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261110(CHEMBL493982 | Ethyl [(3aR,4aR,8aR,9aS)-9(S)-[(E)-...)
Affinity DataKi:  13nMAssay Description:Antagonist activity at human PAR1 in HCASMC assessed as inhibition of thrombin-induced thymidine incorporationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261112(CHEMBL494816 | propyl (1R,3aR,4aR,6R,8aR,9S,9aS)-9...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261015((3R,3aS,4S,4aR,7R,8aR,9aR,E)-7-amino-4-(2-(5-(3-fl...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261016(CHEMBL447913 | N-((1R,3aR,4aR,6R,8aR,9S,9aS)-1-met...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261113(CHEMBL455020 | tert-butyl (1R,3aR,4aR,6R,8aR,9S,9a...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50261115(CHEMBL506808 | ethyl (1R,3aR,4aR,6R,8aR,9S,9aS)-9-...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50260517(CHEMBL460583 | ethyl (1R,3aR,4aR,6R,8aR,9S,9aS)-9-...)
Affinity DataKi:  367nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50215908((3R,3aS,4S,4aR,8aS,9aR,E)-3-methyl-4-(2-(5-(pyrrol...)
Affinity DataKi:  487nMAssay Description:Binding affinity to cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50215910((3R,3aS,4S,4aR,8aS,9aR,E)-3-methyl-4-(2-(5-(pyridi...)
Affinity DataKi:  1.30E+4nMAssay Description:Binding affinity to cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50380022(CHEMBL2012509)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [3H]haTRAP from human PAR1 after 1 hr by TopCount scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50179567((+)-(3R,3aS,4S,4aR,8aS,9aR)-4-(2-(6-hydroxyquinoli...)
Affinity DataIC50:  6.30nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50380014(CHEMBL2012500)
Affinity DataIC50:  6.40nMAssay Description:Displacement of [3H]haTRAP from human PAR1 after 1 hr by TopCount scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50212443((3aR,4R,9aS,E)-7,8-difluoro-4-(2-(5-(3-fluoropheny...)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]haTRAP from PAR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50212440((3aR,4R,9aS,E)-4-(2-(5-(3-fluorophenyl)pyridin-2-y...)
Affinity DataIC50:  7.5nMAssay Description:Displacement of [3H]haTRAP from PAR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50212436((3aR,4R,9aS,E)-7-fluoro-4-(2-(5-(3-fluorophenyl)py...)
Affinity DataIC50:  7.60nMAssay Description:Displacement of [3H]haTRAP from PAR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50222017(1R,3aR,4aS,8aS,9S,9aS)-6-(cyclopropylcarbonyl)-9-[...)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50222041((1R,3aR,4aS,8aS,9S,9aS)-ethyl decahydro-1-methyl-3...)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50380018(CHEMBL2012505)
Affinity DataIC50:  8.10nMAssay Description:Displacement of [3H]haTRAP from human PAR1 after 1 hr by TopCount scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50380023(CHEMBL2012510)
Affinity DataIC50:  8.60nMAssay Description:Displacement of [3H]haTRAP from human PAR1 after 1 hr by TopCount scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50380004(CHEMBL2012489)
Affinity DataIC50:  8.80nMAssay Description:Displacement of [3H]haTRAP from human PAR1 after 1 hr by TopCount scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50212453((3aR,4R,9aS,E)-4-(2-(5-(3-chlorophenyl)pyridin-2-y...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]haTRAP from PAR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50212430((3aR,4R,9aS,E)-6-fluoro-4-(2-(5-(3-fluorophenyl)py...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]haTRAP from PAR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50212429((3aR,4R,9aS,E)-4-(2-(5-(3-(trifluoromethyl)phenyl)...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]haTRAP from PAR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50173437((3R,3aS,4S,4aR,8aS,9aR)-4-{(E)-2-[5-(3-Chloro-phen...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibitory concentration aganist human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50222015((1R,3aR,4aS,8aS,9S,9aS)-decahydro-1-methyl-3-oxo-9...)
Affinity DataIC50:  10.5nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50222030((1R,3aR,4aS,8aS,9S,9aS)-decahydro-1-methyl-3-oxo-9...)
Affinity DataIC50:  11nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50173419((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-{(E)-2-[5-(3-tr...)
Affinity DataIC50:  11nMAssay Description:Displacement of [3H]haTRAP from human PAR1 receptor in platelet membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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