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Found 78 with Last Name = 'ahmed' and Initial = 'em'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512093(CHEMBL4442101)
Affinity DataIC50:  16nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512095(CHEMBL4435643)
Affinity DataIC50:  18nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512097(CHEMBL4536976)
Affinity DataIC50:  19nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512102(CHEMBL4465207)
Affinity DataIC50:  20nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512098(CHEMBL4574755)
Affinity DataIC50:  37nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512100(CHEMBL4444603)
Affinity DataIC50:  49nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512096(CHEMBL4547736)
Affinity DataIC50:  52nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  68nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512101(CHEMBL4466102)
Affinity DataIC50:  90nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50531285(CHEMBL4581121)
Affinity DataIC50:  98nMAssay Description:Inhibition of SIRT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50531285(CHEMBL4581121)
Affinity DataIC50:  98nMAssay Description:Inhibition of SIRT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512092(CHEMBL4450213)
Affinity DataIC50:  98nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512099(CHEMBL4529760)
Affinity DataIC50:  103nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512094(CHEMBL4564780)
Affinity DataIC50:  135nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512096(CHEMBL4547736)
Affinity DataIC50:  210nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  220nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512098(CHEMBL4574755)
Affinity DataIC50:  240nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512099(CHEMBL4529760)
Affinity DataIC50:  270nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512093(CHEMBL4442101)
Affinity DataIC50:  370nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001212(CHEMBL3236732)
Affinity DataIC50:  390nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512094(CHEMBL4564780)
Affinity DataIC50:  390nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50148800(CHEMBL3770486)
Affinity DataIC50:  400nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50148800(CHEMBL3770486)
Affinity DataIC50:  400nMAssay Description:Inhibition of human SIRT2 (25-389 aa) expressed in Escherichia coli BL21 using ZMAL (Z-Lys(Acetyl)-AMC) as substrate incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50148800(CHEMBL3770486)
Affinity DataIC50:  400nMAssay Description:Inhibition of human SIRT2 (25-389 aa) expressed in Escherichia coli BL21 using ZMAL (Z-Lys(Acetyl)-AMC) as substrate incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50148800(CHEMBL3770486)
Affinity DataIC50:  400nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512095(CHEMBL4435643)
Affinity DataIC50:  450nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512101(CHEMBL4466102)
Affinity DataIC50:  460nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001211(CHEMBL3236731)
Affinity DataIC50:  500nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512092(CHEMBL4450213)
Affinity DataIC50:  530nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512100(CHEMBL4444603)
Affinity DataIC50:  540nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512102(CHEMBL4465207)
Affinity DataIC50:  700nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001213(CHEMBL3236733)
Affinity DataIC50:  720nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50512097(CHEMBL4536976)
Affinity DataIC50:  750nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001222(CHEMBL3236734)
Affinity DataIC50:  840nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50531283(CHEMBL4452438)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50531283(CHEMBL4452438)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001212(CHEMBL3236732)
Affinity DataIC50:  2.86E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001211(CHEMBL3236731)
Affinity DataIC50:  3.15E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001213(CHEMBL3236733)
Affinity DataIC50:  4.02E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50531286(CHEMBL4568936)
Affinity DataIC50:  4.27E+3nMAssay Description:Inhibition of SIRT1 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50531286(CHEMBL4568936)
Affinity DataIC50:  4.27E+3nMAssay Description:Inhibition of SIRT1 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50001222(CHEMBL3236734)
Affinity DataIC50:  4.46E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50531286(CHEMBL4568936)
Affinity DataIC50:  4.98E+3nMAssay Description:Inhibition of SIRT2 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50531286(CHEMBL4568936)
Affinity DataIC50:  4.98E+3nMAssay Description:Inhibition of SIRT2 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50531288(CHEMBL4553883)
Affinity DataIC50:  6.77E+3nMAssay Description:Inhibition of SIRT2 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50531288(CHEMBL4553883)
Affinity DataIC50:  6.77E+3nMAssay Description:Inhibition of SIRT2 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50531287(CHEMBL4454236)
Affinity DataIC50:  8.57E+3nMAssay Description:Inhibition of SIRT2 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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