Affinity DataIC50: 16nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of SIRT1 (unknown origin)More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of SIRT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 103nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human SIRT2 (25-389 aa) expressed in Escherichia coli BL21 using ZMAL (Z-Lys(Acetyl)-AMC) as substrate incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human SIRT2 (25-389 aa) expressed in Escherichia coli BL21 using ZMAL (Z-Lys(Acetyl)-AMC) as substrate incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate preincubated with enzyme for 10 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 840nMAssay Description:Inhibition of ovine COX2 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.15E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 4.02E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of SIRT1 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of SIRT1 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.46E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate assessed as conversion of PGH2 to PGF2alpha after 10 mins by EIAMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 4.98E+3nMAssay Description:Inhibition of SIRT2 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 4.98E+3nMAssay Description:Inhibition of SIRT2 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 6.77E+3nMAssay Description:Inhibition of SIRT2 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 6.77E+3nMAssay Description:Inhibition of SIRT2 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cairo University
Curated by ChEMBL
Cairo University
Curated by ChEMBL
Affinity DataIC50: 8.57E+3nMAssay Description:Inhibition of SIRT2 (unknown origin) using fluorogenic substrate assessed as deacetylase activity incubated for 45 mins by fluorescence assayMore data for this Ligand-Target Pair