Affinity DataKi: 25nMAssay Description:Inhibition of carbonic anhydrase 1 in human RBC cells by SDS-PAGE/fluorescence gel imagingMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
Affinity DataKi: 3.30E+3nMAssay Description:Inhibition of carbonic anhydrase 1 in human RBC cells by SDS-PAGE/fluorescence gel imagingMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Inhibition of carbonic anhydrase 1 in human RBC cells by SDS-PAGE/fluorescence gel imagingMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Antagonist activity at recombinant human LPA1 expressed in CHO cell membranes pretreated for 24 hrs prior to Fura-2-AM dye addition for 1 hr followed...More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Antagonist activity at recombinant human LPA1 expressed in CHO cell membranes pretreated for 24 hrs prior to Fura-2-AM dye addition for 1 hr followed...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.62nMAssay Description:Antagonist activity at human CCR5 expressed in HOS cells assessed as inhibition of cell fusion with HIV gp120 expressing HEK293 cells by LTR lucifera...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Displacement of MIP-1alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at human CCR5 expressed in CHO cells assessed as inhibition of MIP-1alpha-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair