Affinity DataKi: 3.10nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenate after 2.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenate after 2.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenate after 2.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenate after 2.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenate after 2.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenate after 2.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenate after 2.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 9.40nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenate after 2.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenate after 2.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenate after 2.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenate after 2.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenate after 2.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Displacement of [3H]N-methylspiperone from D2 after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Displacement of [3H]LSD from 5-HT2B after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataKi: 147nMAssay Description:Displacement of [3H]LSD from 5-HT2B after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataKi: 155nMAssay Description:Displacement of [3H]LSD from 5-HT2B after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataKi: 243nMAssay Description:Displacement of [3H]LSD from 5-HT2B after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataKi: 275nMAssay Description:Displacement of [3H]LSD from 5-HT2B after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataKi: 290nMAssay Description:Displacement of [3H]LSD from 5-HT2B after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataKi: 310nMAssay Description:Displacement of [3H]LSD from 5-HT2B after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataKi: 332nMAssay Description:Displacement of [3H]LSD from 5-HT2B after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataKi: 343nMAssay Description:Displacement of [3H]LSD from 5-HT2B after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataKi: 352nMAssay Description:Displacement of [3H]LSD from 5-HT2B after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 432nMAssay Description:Displacement of [3H]N-methylspiperone from D2 after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataKi: 463nMAssay Description:Displacement of [3H]LSD from 5-HT2B after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 484nMAssay Description:Displacement of [3H]N-methylspiperone from D2 after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 556nMAssay Description:Displacement of [3H]N-methylspiperone from D2 after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataKi: 628nMAssay Description:Displacement of [3H]LSD from 5-HT2B after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.03E+3nMAssay Description:Displacement of [3H]N-methylspiperone from D2 after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.65E+3nMAssay Description:Displacement of [3H]N-methylspiperone from D2 after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.79E+3nMAssay Description:Displacement of [3H]N-methylspiperone from D2 after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.87E+3nMAssay Description:Displacement of [3H]N-methylspiperone from D2 after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from D2 after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 1.79E+5nMAssay Description:Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 2.71E+5nMAssay Description:Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 2.93E+5nMAssay Description:Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: 6.66E+5nMAssay Description:Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysisMore data for this Ligand-Target Pair
TargetKynurenine--oxoglutarate transaminase 1(Homo sapiens (Human))
The University Of Sydney
Curated by ChEMBL
The University Of Sydney
Curated by ChEMBL
Affinity DataIC50: >6.00E+6nMAssay Description:Inhibition of human recombinant KAT1 after 20 mins by RP-HPLC analysisMore data for this Ligand-Target Pair