Affinity DataKi: 6.30nMAssay Description:Inhibition of recombinant Pneumocystis carinii DHFR expressed in Escherichia coli Rosetta Gami B (DE3) by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibition of recombinant human DHFR expressed in Escherichia coli Rosetta Gami B (DE3) by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of adenosine kinase (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR intracellular domain (unknown origin) purified from a baculovirus expression system using Biotin-(amino hexonoic acid)-EEEEYFELVAK...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of ErbB-2 intracellular domain (unknown origin) purified from a baculovirus expression system using Biotin-(amino hexonoic acid)-EEEEYFELV...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of Pneumocystis carinii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of ErbB-2 intracellular domain (unknown origin) purified from a baculovirus expression system using Biotin-(amino hexonoic acid)-EEEEYFELV...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of EGFR intracellular domain (unknown origin) purified from a baculovirus expression system using Biotin-(amino hexonoic acid)-EEEEYFELVAK...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of EGFR intracellular domain (unknown origin) purified from a baculovirus expression system using Biotin-(amino hexonoic acid)-EEEEYFELVAK...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of ErbB-2 intracellular domain (unknown origin) purified from a baculovirus expression system using Biotin-(amino hexonoic acid)-EEEEYFELV...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of ErbB-2 intracellular domain (unknown origin) purified from a baculovirus expression system using Biotin-(amino hexonoic acid)-EEEEYFELV...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of EGFR intracellular domain (unknown origin) purified from a baculovirus expression system using Biotin-(amino hexonoic acid)-EEEEYFELVAK...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrateMore data for this Ligand-Target Pair