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Found 48 with Last Name = 'al-izki' and Initial = 's'
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  920nMAssay Description:Inhibition of human Nav1.5 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  2.55E+3nMAssay Description:Inhibition of human Nav1.1 assessed as inactivated-state block using double pulse protocol by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  3.02E+3nMAssay Description:Inhibition of human Nav1.7 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  3.32E+3nMAssay Description:Inhibition of human Nav1.6 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  3.54E+3nMAssay Description:Inhibition of human Nav1.2 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  3.77E+3nMAssay Description:Inhibition of human Nav1.8 assessed as inactivated-state block using double pulse protocol by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  4.58E+3nMAssay Description:Inhibition of human Nav1.4 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  4.76E+3nMAssay Description:Inhibition of human Nav1.3 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  4.82E+3nMAssay Description:Inhibition of human Nav1.7 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  5.64E+3nMAssay Description:Inhibition of human Nav1.7 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  5.66E+3nMAssay Description:Inhibition of human Nav1.8 assessed as 10 Hz block using double pulse protocol by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  6.34E+3nMAssay Description:Inhibition of human Nav1.8 assessed as tonic block using double pulse protocol by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  8.54E+3nMAssay Description:Inhibition of human Nav1.1 assessed as 10 Hz block using double pulse protocol by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of human Nav1.4 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of human Nav1.7 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of human Nav1.5 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of human Nav1.1 assessed as tonic block using double pulse protocol by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of human Nav1.4 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human Nav1.5 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human Nav1.1 assessed as inactivated-state block using double pulse protocol by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of human Nav1.3 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human Nav1.4 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human Nav1.6 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  2.41E+4nMAssay Description:Inhibition of human Nav1.2 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human Nav1.8 assessed as inactivated-state block using double pulse protocol by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human Nav1.7 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of human Nav1.2 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  3.22E+4nMAssay Description:Inhibition of human Nav1.6 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of human Nav1.5 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of human Nav1.7 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of human Nav1.2 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human Nav1.4 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of human Nav1.2 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of human Nav1.5 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of human Nav1.2 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50:  9.70E+4nMAssay Description:Inhibition of human Nav1.3 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.4 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.8 assessed as 10 Hz block using double pulse protocol by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.1 assessed as 10 Hz block using double pulse protocol by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.8 assessed as tonic block using double pulse protocol by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.3 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.6 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.6 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008745(CHEMBL3236329)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.6 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.3 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.3 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.5 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Nav1.1 assessed as tonic block using double pulse protocol by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed