Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Affinity DataIC50: 69nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Affinity DataIC50: 77nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 149nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Affinity DataIC50: 151nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 161nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 164nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Affinity DataIC50: 169nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Affinity DataIC50: 173nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Affinity DataIC50: 185nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 186nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Affinity DataIC50: 201nMAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Affinity DataIC50: 202nMAssay Description:Inhibition of human placental 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 mins by radio flow detector-based HPLC analysis in presenc...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 222nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Affinity DataIC50: 243nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 246nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 262nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 265nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 278nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 326nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 335nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Affinity DataIC50: 336nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Affinity DataIC50: 342nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 371nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 371nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 394nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Affinity DataIC50: 413nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Affinity DataIC50: 455nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Affinity DataIC50: 471nMAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 482nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 494nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 496nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 559nMAssay Description:Tritiated E2 was incubated with 17beta-HSD2, cofactor, and inhibitor. The amount of labeled E1 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 594nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 602nMAssay Description:Tritiated E2 was incubated with 17beta-HSD2, cofactor, and inhibitor. The amount of labeled E1 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 639nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 745nMAssay Description:Tritiated E2 was incubated with 17beta-HSD2, cofactor, and inhibitor. The amount of labeled E1 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University
Curated by ChEMBL
Saarland University
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by ra...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair