TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 0.0170nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 0.106nMAssay Description:Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 0.127nMAssay Description:Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 0.410nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 0.460nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 0.640nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Displacement of [3H]nisoxetine from NET in rat brain membranesMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 0.930nMAssay Description:Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 0.960nMAssay Description:Displacement of [3H]GBR-12935 from dopamine transporter of rat caudate-putamenMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 1.06nMAssay Description:Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.13nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.56nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.67nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 1.84nMAssay Description:Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 2.14nMAssay Description:Displacement of [3H]methoxy-PEPY from rat mGluR5 expressed in human HEK-293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.47nMAssay Description:Displacement of [3H]nisoxetine from NET in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]nisoxetine from norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 3.51nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 3.76nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 3.91nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 4.02nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 4.42nMAssay Description:Displacement of [3H]GBR-12935 from dopamine transporter of rat caudate-putamenMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 4.56nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 5.15nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 6.40nMAssay Description:Displacement of [3H]GBR-12935 from dopamine transporter of rat caudate-putamenMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 6.43nMAssay Description:Displacement of [3H]GBR-12935 from dopamine transporter of rat caudate-putamenMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 7.14nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 11.3nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 12.1nMAssay Description:Displacement of [3H]GBR-12935 from dopamine transporter of rat caudate-putamenMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 12.2nMAssay Description:Displacement of [3H]GBR-12935 from dopamine transporter of rat caudate-putamenMore data for this Ligand-Target Pair
Affinity DataKi: 12.7nMAssay Description:Displacement of [3H]nisoxetine from NET in rat caudate-putamenMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Institute For Neurodegenerative Disorders
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assayMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 14.2nMAssay Description:Displacement of [3H]GBR from DAT in rat brain membranesMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 14.2nMAssay Description:Displacement of [3H]GBR-12935 from DAT in rat rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 15.4nMAssay Description:Displacement of [3H]nisoxetine from NET in rat brain membranesMore data for this Ligand-Target Pair