Affinity DataIC50: 15nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of GlyT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 154nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human ERG potassium channel by patch-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.73E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.76E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.76E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity at human mu opioid receptor in BHK cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair