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Found 27 with Last Name = 'alfonsi' and Initial = 'r'
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468707(CHEMBL4290935)
Affinity DataIC50:  290nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468718(CHEMBL4290044)
Affinity DataIC50:  2.58E+3nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468709(CHEMBL4285647)
Affinity DataIC50:  2.87E+3nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468720(CHEMBL4293248)
Affinity DataIC50:  3.48E+3nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468708(CHEMBL4291101)
Affinity DataIC50:  3.61E+3nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468711(CHEMBL4286606)
Affinity DataIC50:  3.72E+3nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468709(CHEMBL4285647)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468715(CHEMBL4289866)
Affinity DataIC50:  6.92E+3nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468706(CHEMBL4279181)
Affinity DataIC50:  6.97E+3nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468716(CHEMBL4289632)
Affinity DataIC50:  1.05E+4nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468706(CHEMBL4279181)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468718(CHEMBL4290044)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50233217(CHEMBL4090942)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of Bodipy-cyclopamine binding to mouse FLAG-tagged Smo expressed in HEK293 cells after 3 hrs by Hoechst staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468712(CHEMBL4279361)
Affinity DataIC50:  1.60E+4nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468711(CHEMBL4286606)
Affinity DataIC50:  1.71E+4nMAssay Description:Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468710(CHEMBL4281758)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468708(CHEMBL4291101)
Affinity DataIC50:  2.12E+4nMAssay Description:Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50233218(CHEMBL4063037)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of Bodipy-cyclopamine binding to mouse FLAG-tagged Smo expressed in HEK293 cells after 3 hrs by Hoechst staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468716(CHEMBL4289632)
Affinity DataIC50:  2.67E+4nMAssay Description:Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468714(CHEMBL4282816)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468713(CHEMBL4293424)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468717(CHEMBL4286204)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468710(CHEMBL4281758)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468719(CHEMBL4278297)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468715(CHEMBL4289866)
Affinity DataIC50:  3.92E+4nMAssay Description:Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468720(CHEMBL4293248)
Affinity DataIC50:  5.53E+4nMAssay Description:Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Mus musculus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50468707(CHEMBL4290935)
Affinity DataIC50:  5.77E+4nMAssay Description:Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed