TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Affinity for alphaIIb-beta3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Effect against adhesion of HEK 293 cells transfected with human alpha-v beta-3 to vitronectin coated platesMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity evaluated against vitronectin receptor (alphaV-beta3) receptorMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Affinity for vitronectin receptor, integrin alphaV-beta3More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Effect against adhesion of HEK 293 cells transfected with human alpha-v beta-3 to vitronectin coated platesMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Effect against adhesion of HEK 293 cells transfected with human alpha-v beta-3 to vitronectin coated platesMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Affinity for alphaIIb-beta3 receptorMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of [3H]-SKF- 107260 binding to purified GPIIb/IIIa from human platelets reconstituted in liposomesMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Affinity for platelet fibrinogen receptor, integrin alpha IIb/beta3More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Antagonistic activity for human vitronectin receptor (alphaV-beta3) from plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Effect against adhesion of HEK 293 cells transfected with human alpha-v beta-3 to vitronectin coated platesMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Affinity for vitronectin receptor, integrin alphaV-beta3More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Effect against adhesion of HEK 293 cells transfected with human alpha-v beta-3 to vitronectin coated platesMore data for this Ligand-Target Pair