TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories
Curated by PDSP Ki Database
Merck Sharp And Dohme Research Laboratories
Curated by PDSP Ki Database
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by PDSP Ki Database
Merck Sharp And Dohme Research Laboratories
Curated by PDSP Ki Database
Affinity DataKi: 12nMAssay Description:Un-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 55nM ΔG°: -41.4kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Un-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 64nM ΔG°: -41.1kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 92nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 95nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 102nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 108nM ΔG°: -39.8kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
Affinity DataKi: 111nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 115nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 119nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 119nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 126nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 128nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 129nM ΔG°: -39.3kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
Affinity DataKi: 136nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 144nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 149nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 159nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 160nM ΔG°: -38.8kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
Affinity DataKi: 166nM ΔG°: -38.7kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
Affinity DataKi: 197nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 203nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 208nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 215nM ΔG°: -38.1kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
Affinity DataKi: 219nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 246nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 259nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 288nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 318nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 318nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 337nM ΔG°: -36.9kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
Affinity DataKi: 349nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 379nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 2 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 384nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 411nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 435nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 448nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 461nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 485nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 487nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Non-competitive inhibition of human erythrocytes carbonic anhydrase 1 esterase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 494nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 508nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair
Affinity DataKi: 521nM ΔG°: -35.9kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
Affinity DataKi: 522nMAssay Description:CA activity was measured according to the method described by Verpoorte et al. in inhibition studies, spectrophotometrically [Biochem., 242:4221-4229...More data for this Ligand-Target Pair