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Found 90 with Last Name = 'almeida' and Initial = 'r'
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50410534(CHEMBL83116)
Affinity DataIC50:  1.59E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50410534(CHEMBL83116)
Affinity DataIC50:  1.59E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197882(CHEMBL3959466)
Affinity DataIC50:  2.02E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197882(CHEMBL3959466)
Affinity DataIC50:  2.04E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
Affinity DataIC50:  2.19E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
Affinity DataIC50:  2.20E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197881(CHEMBL3890392)
Affinity DataIC50:  2.49E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197881(CHEMBL3890392)
Affinity DataIC50:  2.51E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301372((E/Z)-3-(4-nitrophenylimino)indolin-2-one | CHEMBL...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197883(CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Co...)
Affinity DataIC50:  3.09E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197883(CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Co...)
Affinity DataIC50:  3.10E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301374(2,4,6-Triiodo-phenol | 2,4,6-Triiodo-phenol(TIP) |...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301380((E/Z)-1-methyl-3-(p-tolylimino)indolin-2-one | CHE...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM10304(1-methyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL6...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301373((E/Z)-1-methyl-3-(4-nitrophenylimino)indolin-2-one...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197884(CHEMBL3969733)
Affinity DataIC50:  7.10E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301381((E/Z)-3-(4-methoxyphenylimino)-1-methylindolin-2-o...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50189601((E)-3-(4-methoxyphenylimino)indolin-2-one | (E/Z)-...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301375(3,3',5,5'-tetraiodo-L-thyronine | 3,5,3',5'-tetrai...)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301377((E/Z)-1-methyl-3-(phenylimino)indolin-2-one | CHEM...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301386((E/Z)-3-(4-iodophenylimino)indolin-2-one | CHEMBL5...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301389((E/Z)-5-bromo-3-(4-iodophenylimino)indolin-2-one |...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301390((E/Z)-5-iodo-3-(4-iodophenylimino)indolin-2-one | ...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301385((E/Z)-3-(4-methoxyphenylimino)-5-nitroindolin-2-on...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301384((E/Z)-5-iodo-3-(4-methoxyphenylimino)indolin-2-one...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301379((E/Z)-3-(p-tolylimino)indolin-2-one | CHEMBL571380)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301383((E/Z)-5-bromo-3-(4-methoxyphenylimino)indolin-2-on...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301378((E/Z)-5-iodo-3-(phenylimino)indolin-2-one | CHEMBL...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50198047((E/Z)-3-(phenylimino)indolin-2-one | 3-(phenylimin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM11022(2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301376((E/Z)-3-(4-iodophenylimino)-5-nitroindolin-2-one |...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301382((E/Z)-3-(4-methoxyphenylimino)-5-methylindolin-2-o...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301387((E/Z)-3-(4-iodophenylimino)-1-methylindolin-2-one ...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50301388((E/Z)-3-(4-iodophenylimino)-5-methylindolin-2-one ...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50240347((9,12,15)-linolenic acid | (9Z,12Z,15Z)-octadeca-9...)
Affinity DataEC50:  3.16E+3nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50275510(3-(4-(Phenylethynyl)phenyl)propanoic acid | CHEMBL...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157566(CHEMBL3785667)
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157567(CHEMBL3785789)
Affinity DataEC50:  1.45E+3nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157568(CHEMBL3787580)
Affinity DataEC50:  389nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157569(CHEMBL3787151)
Affinity DataEC50:  1.82E+3nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157571(CHEMBL3786964)
Affinity DataEC50:  5.01E+3nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157600(CHEMBL3787110)
Affinity DataEC50:  490nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157601(CHEMBL3786418)
Affinity DataEC50:  513nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157602(CHEMBL3787165)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157603(CHEMBL3786524)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157613(CHEMBL3785544)
Affinity DataEC50:  417nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157614(CHEMBL3786972)
Affinity DataEC50:  83nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157615(CHEMBL3787463)
Affinity DataEC50:  81nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157616(CHEMBL3786526)
Affinity DataEC50:  209nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University Of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50157617(CHEMBL3785764)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells measured for 50 intervals of 0.4 secs by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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