TargetKappa-type opioid receptor(Homo sapiens (Human))
National Cancer Institute (Ba, Mm, Sl, Sva)
Curated by ChEMBL
National Cancer Institute (Ba, Mm, Sl, Sva)
Curated by ChEMBL
Affinity DataKi: 210nMAssay Description:Binding affinity towards human kappa opioid receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National Cancer Institute (Ba, Mm, Sl, Sva)
Curated by ChEMBL
National Cancer Institute (Ba, Mm, Sl, Sva)
Curated by ChEMBL
Affinity DataKi: 483nMAssay Description:Binding affinity towards human adenosine A3 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Homo sapiens (Human))
National Cancer Institute (Ba, Mm, Sl, Sva)
Curated by ChEMBL
National Cancer Institute (Ba, Mm, Sl, Sva)
Curated by ChEMBL
Affinity DataKi: 6.82E+3nMAssay Description:Binding affinity towards human adenosine A3 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Mus musculus)
National Cancer Institute (Ba, Mm, Sl, Sva)
Curated by ChEMBL
National Cancer Institute (Ba, Mm, Sl, Sva)
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards mouse adenosine A3 receptorMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on mitoxantrone-induced cytotoxicity by measuring mitox...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on mitoxantrone-induced cytotoxicity by measuring mitox...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on mitoxantrone-induced cytotoxicity by measuring mitox...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on mitoxantrone-induced cytotoxicity by measuring mitox...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human DDR2 using KKSRGDYMTMQIG peptide substrateMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on topotecan-induced cytotoxicity by measuring topoteca...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on mitoxantrone-induced cytotoxicity by measuring mitox...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of CYP3A4 (unknown origin) expressed in baculosomesMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on topotecan-induced cytotoxicity by measuring topoteca...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on topotecan-induced cytotoxicity by measuring topoteca...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on topotecan-induced cytotoxicity by mea...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on topotecan-induced cytotoxicity by measuring topoteca...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human PDGFRbeta using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on mitoxantrone-induced cytotoxicity by ...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on mitoxantrone-induced cytotoxicity by ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human PDGFRalpha using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on mitoxantrone-induced cytotoxicity by ...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on mitoxantrone-induced cytotoxicity by ...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on topotecan-induced cytotoxicity by measuring topoteca...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]-IAAP from human P-gp expressed in high five insect cell membrane vesicles preincubated for 10 mins followed by photocrosslinki...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 108nMAssay Description:Inhibition of human LCK using poly[Glu:Tyr] (4:1) peptide substrateMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on topotecan-induced cytotoxicity by mea...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 136nMAssay Description:Inhibition of human ABL1 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on topotecan-induced cytotoxicity by mea...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 148nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on topotecan-induced cytotoxicity by mea...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human S1-M1-80 cells assessed as effect on topotecan-induced cytotoxicity by meas...More data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 179nMAssay Description:Inhibition of human DDR2 using KKSRGDYMTMQIG peptide substrateMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human S1-M1-80 cells assessed as effect on topotecan-induced cytotoxicity by meas...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 367nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on topotecan-induced cytotoxicity by mea...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human S1-M1-80 cells assessed as effect on topotecan-induced cytotoxicity by meas...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of human ABCG2 in human R5 cells assessed as inhibition of mitoxantrone efflux measured by flow cytometric analysisMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 442nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human H460-MX20 cells assessed as effect on mitoxantrone-induced cytotoxicity by ...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human S1-M1-80 cells assessed as effect on mitoxantrone-induced cytotoxicity by m...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human ABCG2 in human R5 cells assessed as inhibition of mitoxantrone efflux measured by flow cytometric analysisMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Taipei Chang Gung Memorial Hospital
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Reversal of ABCG2 (unknown origin)-mediated multidrug resistance in human S1-M1-80 cells assessed as effect on topotecan-induced cytotoxicity by meas...More data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 653nMAssay Description:Inhibition of human DDR2 using KKSRGDYMTMQIG peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Displacement of [125I]IAPP from ABCB1 (unknown origin) expressed in High Five insect cell membrane at >5 uM preincubated for 10 mins by autoradiograp...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
National Center For Advancing Translational Sciences
Curated by ChEMBL
National Center For Advancing Translational Sciences
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of human ABL1 using EAIYAAPFAKKK peptide substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Displacement of [125I]-IAAP from human P-gp expressed in high five insect cell membrane vesicles preincubated for 10 mins followed by photocrosslinki...More data for this Ligand-Target Pair