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maximum 50k data
Found 463 with Last Name = 'bannen' and Initial = 'lc'
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM609993(1-N'-[3-chloro-4-[6-methoxy- 7-(3-morpholin-4- ylp...)
Affinity DataIC50: <10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [H473-A894](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM609994(1-N'-[3-fluoro-4-[6-methoxy- 7-(3-morpholin-4- ylp...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM609994(1-N'-[3-fluoro-4-[6-methoxy- 7-(3-morpholin-4- ylp...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM609994(1-N'-[3-fluoro-4-[6-methoxy- 7-(3-morpholin-4- ylp...)
Affinity DataIC50: <10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610009(1-N-[4-(6-carbamoyl-7- methoxyquinazolin-4- yl)oxy...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610010(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6-(2-pyrr...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [H473-A894](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610013(1-N'-(4-fluorophenyl)-1- N-[4-[7-methoxy-6-[[(2R)-...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610013(1-N'-(4-fluorophenyl)-1- N-[4-[7-methoxy-6-[[(2R)-...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610013(1-N'-(4-fluorophenyl)-1- N-[4-[7-methoxy-6-[[(2R)-...)
Affinity DataIC50: <10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [H473-A894](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610013(1-N'-(4-fluorophenyl)-1- N-[4-[7-methoxy-6-[[(2R)-...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610013(1-N'-(4-fluorophenyl)-1- N-[4-[7-methoxy-6-[[(2R)-...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [H473-A894](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610015(1-N-[4-[(6,7-dimethoxy- 1,5-naphthyridin-4- yl)oxy...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610015(1-N-[4-[(6,7-dimethoxy- 1,5-naphthyridin-4- yl)oxy...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610015(1-N-[4-[(6,7-dimethoxy- 1,5-naphthyridin-4- yl)oxy...)
Affinity DataIC50: <10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [H473-A894](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610018(1-N'-[4-[(6,7-dimethoxy- 1,5-naphthyridin-4-yl)oxy...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610018(1-N'-[4-[(6,7-dimethoxy- 1,5-naphthyridin-4-yl)oxy...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610018(1-N'-[4-[(6,7-dimethoxy- 1,5-naphthyridin-4-yl)oxy...)
Affinity DataIC50: <10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610019(1-N'-[3-chloro-4-[(6,7- dimethoxy- 1,5-naphthyridi...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM610019(1-N'-[3-chloro-4-[(6,7- dimethoxy- 1,5-naphthyridi...)
Affinity DataIC50: <10nMAssay Description:Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesium acetate, an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [473-894,Q764R](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM605720(US11673897, Compound 10 | methyl 4-[5-[[1-[(4- flu...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM605720(US11673897, Compound 10 | methyl 4-[5-[[1-[(4- flu...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM605720(US11673897, Compound 10 | methyl 4-[5-[[1-[(4- flu...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEQ ID NO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [473-894,Q764R](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM605721(US11673897, Compound 11 | methyl 4-[3-chloro-5-[[1...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM605721(US11673897, Compound 11 | methyl 4-[3-chloro-5-[[1...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM605721(US11673897, Compound 11 | methyl 4-[3-chloro-5-[[1...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEQ ID NO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM605724(1-N'-[6-(6-carbamoyl-7- methoxyquinolin-4-yl)oxypy...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM605724(1-N'-[6-(6-carbamoyl-7- methoxyquinolin-4-yl)oxypy...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEQ ID NO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [473-894,Q764R](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM605726(1-N'-[6-(6-carbamoyl-7- methoxyquinolin-4-yl)oxy-5...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM605726(1-N'-[6-(6-carbamoyl-7- methoxyquinolin-4-yl)oxy-5...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM605726(1-N'-[6-(6-carbamoyl-7- methoxyquinolin-4-yl)oxy-5...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEQ ID NO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [473-894,Q764R](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM605727(1-N-(4-fluorophenyl)-1-N'-[6-[7- methoxy-6-(1H-pyr...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM605727(1-N-(4-fluorophenyl)-1-N'-[6-[7- methoxy-6-(1H-pyr...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM605727(1-N-(4-fluorophenyl)-1-N'-[6-[7- methoxy-6-(1H-pyr...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEQ ID NO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [473-894,Q764R](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM605730(US11673897, Compound 82 | l-N'-[6-[(6,7-dimethoxy-...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEQ ID NO. 43), 10 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM605730(US11673897, Compound 82 | l-N'-[6-[(6,7-dimethoxy-...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor [974-1390,A1209G,V1290L](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM605730(US11673897, Compound 82 | l-N'-[6-[(6,7-dimethoxy-...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEQ ID NO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588246(US11542259, Compound 150 | methyl 4-[4-[[1-[(4- fl...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM588246(US11542259, Compound 150 | methyl 4-[4-[[1-[(4- fl...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588248(1-N-[4-(7-carbamoyl-6- methoxyquinolin-4- yl)oxyph...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM588248(1-N-[4-(7-carbamoyl-6- methoxyquinolin-4- yl)oxyph...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588249(1-N'-(4-fluorophenyl)-1-N- [4-[6-methoxy-7- (methy...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588250(US11542259, Compound 162 | methyl 4-[4-[[1-[(4- fl...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [473-894,Q764R](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM588252(1-N-[4-(7-carbamoylquinolin- 4-yl)oxyphenyl]-1-N'-...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEO ID NO. 43) 10 mM m...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588252(1-N-[4-(7-carbamoylquinolin- 4-yl)oxyphenyl]-1-N'-...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM588252(1-N-[4-(7-carbamoylquinolin- 4-yl)oxyphenyl]-1-N'-...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [473-894,Q764R](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM588253(1-N'-(4-fluorophenyl)-1-N-[4- [7-(methylcarbamoyl)...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEO ID NO. 43) 10 mM m...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588253(1-N'-(4-fluorophenyl)-1-N-[4- [7-(methylcarbamoyl)...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM588253(1-N'-(4-fluorophenyl)-1-N-[4- [7-(methylcarbamoyl)...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase Mer [557-882,H628Q,R794A](Tyrosine-protein kinase Mer)
Exelixis

US Patent
LigandPNGBDBM588254(1-N-[4-[6-(3-cyano-2- fluorophenyl)-7- methoxyquin...)
Affinity DataIC50: <10nMAssay Description:Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIYFEFMGGKK...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO [473-894,Q764R](Homo sapiens (Human))
Exelixis

US Patent
LigandPNGBDBM588255(1-N'-(4-fluorophenyl)-1-N-[4-(7- methoxy-6-pyridin...)
Affinity DataIC50: <10nMAssay Description:Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKSRGDYMTMQIG (SEO ID NO. 43) 10 mM m...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
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