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Found 81 with Last Name = 'bodensieck' and Initial = 'a'
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295926(4'-O-methylhonokiol, MH | 4-methoxyhonokiol | ...)
Affinity DataIC50:  60nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295926(4'-O-methylhonokiol, MH | 4-methoxyhonokiol | ...)
Affinity DataIC50:  100nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295923(4'-Methoxy-3'-(E)-propenyl)-5-(2-propenyl)-bipheny...)
Affinity DataIC50:  200nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295925((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...)
Affinity DataIC50:  600nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295923(4'-Methoxy-3'-(E)-propenyl)-5-(2-propenyl)-bipheny...)
Affinity DataIC50:  700nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50157312(5,3''-Dipropyl-biphenyl-2,4''-diol | 5,3'-Dipropyl...)
Affinity DataIC50:  800nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  900nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295924(4'-Methoxy-3'-(Z)-propenyl)-5-(2-propenyl)-bipheny...)
Affinity DataIC50:  900nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295925((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295924(4'-Methoxy-3'-(Z)-propenyl)-5-(2-propenyl)-bipheny...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295920(4'-Methoxy-5,3'-dipropyl-biphenyl-2ol | CHEMBL5552...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295926(4'-O-methylhonokiol, MH | 4-methoxyhonokiol | ...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50157312(5,3''-Dipropyl-biphenyl-2,4''-diol | 5,3'-Dipropyl...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50391884(CHEMBL463574)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol | 3',5-...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50391887(CHEMBL2147422)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50157312(5,3''-Dipropyl-biphenyl-2,4''-diol | 5,3'-Dipropyl...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295923(4'-Methoxy-3'-(E)-propenyl)-5-(2-propenyl)-bipheny...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol | 3',5-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295921(2-Acetoxy-4'-methoxy-5,3'-di-(2-propenyl)-biphenyl...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50391880(CHEMBL2147423)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295925((E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295924(4'-Methoxy-3'-(Z)-propenyl)-5-(2-propenyl)-bipheny...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50391884(CHEMBL463574)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50391890(CHEMBL2147420)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol | 3',5-...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295922(2,4'-Diacetoxy-5,3'-di-(2-propenyl)-biphenyl | CHE...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295921(2-Acetoxy-4'-methoxy-5,3'-di-(2-propenyl)-biphenyl...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391887(CHEMBL2147422)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295928(2,4'-Dimethoxy-5,3'-dipropyl-biphenyl | CHEMBL5602...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50391890(CHEMBL2147420)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391890(CHEMBL2147420)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50391880(CHEMBL2147423)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295927(2,4'-Dimethoxy-5,3'-di-(2-propenyl)-biphenyl | 5,3...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295920(4'-Methoxy-5,3'-dipropyl-biphenyl-2ol | CHEMBL5552...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391884(CHEMBL463574)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295927(2,4'-Dimethoxy-5,3'-di-(2-propenyl)-biphenyl | 5,3...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391883(CHEMBL2147424)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391880(CHEMBL2147423)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295927(2,4'-Dimethoxy-5,3'-di-(2-propenyl)-biphenyl | 5,3...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50391887(CHEMBL2147422)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50391886(CHEMBL2147421)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391886(CHEMBL2147421)
Affinity DataIC50:  1.95E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295928(2,4'-Dimethoxy-5,3'-dipropyl-biphenyl | CHEMBL5602...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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