TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity for Human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt-]GnRH from human GnRH receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.560nMAssay Description:Displacement of [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt-]GnRH from human GnRH receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.560nMAssay Description:Binding affinity for Human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity towards human gonadotropin releasing hormone receptor using des-Gly10[125I-Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]GnRH as radioligand expresse...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.610nMAssay Description:Binding affinity for Human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.640nMAssay Description:Binding affinity to human GnRHRMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.640nMAssay Description:Displacement of [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt-]GnRH from human GnRH receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:Binding affinity to mouse MC4RMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt-]GnRH from human GnRH receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity to human GnRHRMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt-]GnRH from human GnRH receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Binding affinity to human GnRHRMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt-]GnRH from human GnRH receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity towards human gonadotropin releasing hormone receptor using des-Gly10[125I-Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]GnRH as radioligand expresse...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity for Human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Binding affinity to human GnRHRMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Binding affinity for Human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of [125I][Tyr0]-sauvagine binding to human Corticotropin releasing factor receptor 1 expressed in mouse fibroblast Ltk- cells More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt-]GnRH from human GnRH receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity to human GnRHRMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Binding affinity for Human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Binding affinity towards human gonadotropin releasing hormone receptor using des-Gly10[125I-Tyr5,D-Leu6,NMeLeu7,Pro9-NEt]GnRH as radioligand expresse...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Inhibition of [125I][Tyr0]-sauvagine binding to human Corticotropin releasing factor receptor 1 expressed in mouse fibroblast Ltk- cells More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Binding affinity for Human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Inhibition of [125I]sauvagine binding to corticotropin releasing factor receptor 1 expressed in LtK- cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Inhibition of [125I]-o-CRF binding to CHO cells expressing human CRF1 receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:Binding affinity for Human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:Binding affinity for Human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:Inhibition of [125I]sauvagine binding to corticotropin releasing factor receptor 1 expressed in LtK- cellsMore data for this Ligand-Target Pair