TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.0370nMAssay Description:Displacement of (R)-Na-Diphenylacetyl-Nomega[2-([2,3-3H]-propionylamino)ethyl]aminocarbonyl (4-hydroxybenzyl)-argininamide from NPY1R in human SK-N-M...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Displacement of [3H]propionyl-pNPY from NPY1R (unknown origin)More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Displacement of [3H]propionyl-pNPY from NPY1R (unknown origin)More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.0770nMAssay Description:Displacement of (R)-Na-Diphenylacetyl-Nomega[2-([2,3-3H]-propionylamino)ethyl]aminocarbonyl (4-hydroxybenzyl)-argininamide from NPY1R in human SK-N-M...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]propionyl-pNPY from NPY1R in human HEL cells preincubated for 30 mins followed by radioligand addition at 60 to 90 mins by flow c...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]propionyl-pNPY from NPY1R in human HEL cells preincubated for 30 mins followed by radioligand addition at 60 to 90 mins by flow c...More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]-{Nomega-[N-(4-propanoylaminobutyl)aminocarbonyl]}Arg-Arg-ProTyr-Ile-Leu-OH Tris(hydrotrifluoroacetate) from NTSR1 in human HT-29...More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]-Angiotensin 2 from human placental AT1 receptor expressed in African green monkey COS7 cell membranes after 90 mins by gamma cou...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]UR-MK114 from NPY1R in human SK-N-MC cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]18 from human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]UR-MK114 from NPY1R in human SK-N-MC cells by radioligand binding assayMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Displacement of [3H]propionyl-pNPY from NPY1R in human SK-N-MC cells compound treated immediately post radioligand treatment measured after 2 hrs by ...More data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]-Asp-{Nomega-[N-(4-propanoylaminobutyl)aminocarbonyl]}Arg-ValTyr-Ile-His-Pro-Phe-OH Tris(hydrotrifluoroacetate) from human AT1 re...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]propionyl-pNPY from NPY1R in human HEL cells preincubated for 30 mins followed by radioligand addition at 60 to 90 mins by flow c...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of clobenpropit-BODIPY-630/650 from recombinant human NLuc-fused H3R expressed in HEK293T cells by Nano-BRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]-{Nomega-[N-(4-propanoylaminobutyl)aminocarbonyl]}Arg-Arg-ProTyr-Ile-Leu-OH Tris(hydrotrifluoroacetate) from NTSR1 in human HT-29...More data for this Ligand-Target Pair
Affinity DataKi: 0.263nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293T cells co-expressing CRE-Luc incubated for 60 mins by microbeta sci...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]propionyl-pNPY from NPY1R in human SK-N-MC cells compound treated immediately post radioligand treatment measured after 2 hrs by ...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]propionyl-pNPY from NPY1R in human SK-N-MC cells compound treated immediately post radioligand treatment measured after 2 hrs by ...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]propionyl-pNPY from NPY1R in HEL cells after 60 to 90 mins by flow cytometric analysisMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]propionyl-pNPY from NPY1R in HEL cells after 60 to 90 mins by flow cytometric analysisMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]UR-MK136 from NPY1R in human SK-N-MC cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]18 from human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.339nMAssay Description:Inhibition of UR-DEBa242 binding to human recombinant NLuc/GPCR-fused H3R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]UR-MK136 from NPY1R in human SK-N-MC cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]-{Nomega-[N-(4-propanoylaminobutyl)aminocarbonyl]}Arg-Arg-ProTyr-Ile-Leu-OH Tris(hydrotrifluoroacetate) from NTSR1 in human HT-29...More data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]18 from human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]UR-MK136 from NPY1R in human SK-N-MC cells by radioligand binding assayMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.410nMAssay Description:Displacement of (R)-Na-Diphenylacetyl-Nomega[2-([2,3-3H]-propionylamino)ethyl]aminocarbonyl (4-hydroxybenzyl)-argininamide from NPY1R in human SK-N-M...More data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Displacement of [3H]-{Nomega-[N-(4-propanoylaminobutyl)aminocarbonyl]}Arg-Arg-ProTyr-Ile-Leu-OH Tris(hydrotrifluoroacetate) from NTSR1 in human HT-29...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.420nMAssay Description:Displacement of (R)-Na-Diphenylacetyl-Nomega[2-([2,3-3H]-propionylamino)ethyl]aminocarbonyl (4-hydroxybenzyl)-argininamide from NPY1R in human SK-N-M...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.420nMAssay Description:Displacement of [3H]UR-MK136 from NPY1R in human SK-N-MC cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H](2R,7R)-10 from human NPY Y4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ after 90 mins in presence of sodium-free HE...More data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Displacement of [3H]-{Nomega-[N-(4-propanoylaminobutyl)aminocarbonyl]}Arg-Arg-ProTyr-Ile-Leu-OH Tris(hydrotrifluoroacetate) from NTSR1 in human HT-29...More data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Displacement of [3H]-{Nomega-[N-(4-propanoylaminobutyl)aminocarbonyl]}Arg-Arg-ProTyr-Ile-Leu-OH Tris(hydrotrifluoroacetate) from NTSR1 in human HT-29...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]UR-MK136 from NPY1R in human SK-N-MC cells by radioligand binding assayMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of Cy5-pNPY from human Y1 receptor expressed in HEL cells after 90 to 120 mins by flow cytometryMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of S0586[K4]hpp from human NPY4 receptor expressed in CHO cells co-expressing Gqi5-mtAEQ by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]-UR-PI294 from Galphai2/Gbeta1gamma2-coupled human recombinant H3R expressed in baculovirus infected Sf9 insect cell membranes co...More data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Displacement of [3H]EYE from human NPFF2 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation spectrophotometric countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Binding affinity to human Y4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Displacement of Cy5-[K4]hPP from human Y4 receptor expressed in CHO cells after 90 to 120 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.537nMAssay Description:Inhibition of UR-DEBa242 binding to human recombinant NLuc/GPCR-fused H3R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataKi: 0.560nMAssay Description:Displacement of [3H]UR-MK114 from NPY1R in human SK-N-MC cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.590nMAssay Description:Displacement of [3H]-{Nomega-[N-(4-propanoylaminobutyl)aminocarbonyl]}Arg-Arg-ProTyr-Ile-Leu-OH Tris(hydrotrifluoroacetate) from NTSR1 in human HT-29...More data for this Ligand-Target Pair