Compile Data Set for Download or QSAR
maximum 50k data
Found 105 with Last Name = 'crosby' and Initial = 'rm'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26477(5-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylph...)
Affinity DataIC50:  0.600nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26467(3-({4-[methyl(3-methyl-1H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50:  0.600nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26478(6,7-dimethoxy-N-(3-methyl-1H-indazol-6-yl)quinazol...)
Affinity DataIC50:  1.70nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26470(3-({4-[(2-benzyl-3-methyl-2H-indazol-6-yl)(methyl)...)
Affinity DataIC50:  2.60nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26469(3-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50:  5.60nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26476(5-({2-[(3-bromophenyl)amino]pyrimidin-4-yl}amino)-...)
Affinity DataIC50:  6.30nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26479(4-N-(3-methyl-1H-indazol-6-yl)-2-N-(3,4,5-trimetho...)
Affinity DataIC50:  6.30nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26471(3-({4-[methyl(2-methyl-2H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50:  7.60nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5874(2-Anilino-5-aryloxazole 38 | N-[5-(Ethylsulfonyl)-...)
Affinity DataIC50:  15nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5873(2-Anilino-5-aryloxazole 37 | N-[5-(Ethylsulfonyl)-...)
Affinity DataIC50:  16nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26473(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-5-yl)(meth...)
Affinity DataIC50:  17nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5870(2-Anilino-5-aryloxazole 33 | 4-(2-{[5-(Ethylsulfon...)
Affinity DataIC50:  18nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5862(2-Anilino-5-aryloxazole 25 | 5-(3-Chlorophenyl)-N-...)
Affinity DataIC50:  22nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5875(2-Anilino-5-aryloxazole 39 | N-[5-(Ethylsulfonyl)-...)
Affinity DataIC50:  22nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5859(2-Anilino-5-aryloxazole 20 | N,N-Diethyl-4-methoxy...)
Affinity DataIC50:  23nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5878(2-Anilino-5-aryloxazole 42 | N-[5-(Ethylsulfonyl)-...)
Affinity DataIC50:  25nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5871(2-Anilino-5-aryloxazole 35 | 5-(3-Ethylphenyl)-N-[...)
Affinity DataIC50:  29nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26474(5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM32362(5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]m...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant human GST-tagged CFMS kinase catalytic domain using biotin-EAIYAPFAKKK-NH2 as substrate after 40 mins by NXT scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26468(3-({4-[(1,3-dimethyl-1H-indazol-6-yl)(methyl)amino...)
Affinity DataIC50:  36nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5864(2-Anilino-5-aryloxazole 27 | 5-(3-Methoxyphenyl)-N...)
Affinity DataIC50:  36nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM11445(2-Anilino-5-aryloxazole 46 | N-(cyclopropylmethyl)...)
Affinity DataIC50:  38nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5881(2-Anilino-5-aryloxazole 45 | 5-[3-(2-chlorophenyl)...)
Affinity DataIC50:  39nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5860(2-Anilino-5-aryloxazole 21 | N-[5-(Ethylsulfonyl)-...)
Affinity DataIC50:  50nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5869(2-Anilino-5-aryloxazole 32 | 4-(2-{[5-(ethanesulfo...)
Affinity DataIC50:  51nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26472(3-({4-[(1,2-dimethyl-1H-1,3-benzodiazol-6-yl)(meth...)
Affinity DataIC50:  63nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5876(2-Anilino-5-aryloxazole 40 | N-[5-(Ethylsulfonyl)-...)
Affinity DataIC50:  76nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5877(2-Anilino-5-aryloxazole 41 | N-[5-(Ethylsulfonyl)-...)
Affinity DataIC50:  78nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5879(2-Anilino-5-aryloxazole 43 | 5-(1,1 -Biphenyl-3-yl...)
Affinity DataIC50:  79nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5868(2-Anilino-5-aryloxazole 31 | 5-(4-Fluorophenyl)-N-...)
Affinity DataIC50:  79nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5867(2-Anilino-5-aryloxazole 30 | 5-(4-Chlorophenyl)-N-...)
Affinity DataIC50:  81nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5866(2-Anilino-5-aryloxazole 29 | 5-(4-Methoxyphenyl)-N...)
Affinity DataIC50:  87nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5880(2-Anilino-5-aryloxazole 44 | N-[5-(Ethylsulfonyl)-...)
Affinity DataIC50:  89nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5872(1-[3-(2-{[5-(Ethylsulfonyl)-2-methoxyphenyl]amino}...)
Affinity DataIC50:  91nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5865(2-Anilino-5-aryloxazole 28 | 5-(3-Fluorophenyl)-N-...)
Affinity DataIC50:  93nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5858(2-Anilino-5-aryloxazole 19 | 5-phenyl-N-(3,4,5-tri...)
Affinity DataIC50:  100nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50495951(CHEMBL3121193)
Affinity DataIC50:  130nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS5B Cdelta21 RNA dependent RNA polymerase 316N mutant using biotinylated polyC:oligoG/[alpha-P33]-GTP as...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5856(2-Anilino-5-aryloxazole 17 | N-(3,4-Dimethoxypheny...)
Affinity DataIC50:  140nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5863(2-Anilino-5-aryloxazole 26 | 3-(2-{[5-(ethanesulfo...)
Affinity DataIC50:  141nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50454876(HCV 796 | HCV-796 | Nesbuvir)
Affinity DataIC50:  160nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS5B Cdelta21 RNA dependent RNA polymerase 316N mutant using biotinylated polyC:oligoG/[alpha-P33]-GTP as...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5857(2-Anilino-5-aryloxazole 18 | N-(3,5-Dimethoxypheny...)
Affinity DataIC50:  170nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5861(2-Anilino-5-aryloxazole 24 | 5-(2-Chlorophenyl)-N-...)
Affinity DataIC50:  360nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5848(2-Anilino-5-aryloxazole 9 | N-(2-Methoxyphenyl)-5-...)
Affinity DataIC50:  380nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM26475(2-N,4-N-bis(3-bromophenyl)-5-fluoropyrimidine-2,4-...)
Affinity DataIC50:  400nMpH: 7.5 T: 2°CAssay Description:The assay uses purified baculovirus-expressed GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Gsk

LigandPNGBDBM26470(3-({4-[(2-benzyl-3-methyl-2H-indazol-6-yl)(methyl)...)
Affinity DataIC50:  500nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5851(2-Anilino-5-aryloxazole 12 | N-(3-Hydroxymethylphe...)
Affinity DataIC50:  500nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5854(2-Anilino-5-aryloxazole 15 | 4-[(5-Phenyl-1,3-oxaz...)
Affinity DataIC50:  500nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Gsk

LigandPNGBDBM26467(3-({4-[methyl(3-methyl-1H-indazol-6-yl)amino]pyrim...)
Affinity DataIC50:  700nMpH: 7.4 T: 2°CAssay Description:A range of concentrations of each compound in a 96-well plate were preincubated in buffer containing recombinant human CYP450 microsomal protein and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5852(2-Anilino-5-aryloxazole 13 | N-(3-(Ethylsulfonyl)p...)
Affinity DataIC50:  720nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Gsk

LigandPNGBDBM5847(2-Anilino-5-aryloxazole 8 | 2-[(5-phenyl-1,3-oxazo...)
Affinity DataIC50:  870nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 105 total ) | Next | Last >>
Jump to: