Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Displacement of radiolabled NPY from human Y1R expressed in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity to human H2R expressing Sf9 cells incubated for 60 mins by microbeta scintillation counter methodMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cells by flowcytometryMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cells by flowcytometryMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 97nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: >100nMAssay Description:Displacement of [125I]-aminopotentidine from rat H2R expressed in human COS7 cells incubated for 90 mins gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >100nMAssay Description:Displacement of [125I]-aminopotentidine from rat H2R expressed in human COS7 cells incubated for 90 mins gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Displacement of [3H]-UR-MK114 from Y1R in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 269nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 295nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 302nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 324nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: >400nMAssay Description:Displacement of Dy-635-pNPY from human Y5R expressed in CHO cells by flowcytometryMore data for this Ligand-Target Pair
Affinity DataKi: >500nMAssay Description:Displacement of Cy5-[K4]-hpp from human Y4R expressed in CHO cells by flowcytometryMore data for this Ligand-Target Pair
Affinity DataKi: >500nMAssay Description:Displacement of Dy-635-pNPY from human Y2R expressed in CHO cells by flowcytometryMore data for this Ligand-Target Pair
Affinity DataKi: 1.32E+3nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 2.04E+3nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of Dy-635-pNPY from human Y2R expressed in CHO cells by flowcytometryMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of Cy5-[K4]-hpp from human Y4R expressed in CHO cells by flowcytometryMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of Dy-635-pNPY from human Y5R expressed in CHO cells by flowcytometryMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-tagged JAK2 assessed as inhibition of biotinylated JAK3tide peptide phosphorylation after 60 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-tagged JAK2 assessed as inhibition of biotinylated JAK3tide peptide phosphorylation after 60 mins by caliper mobility shift assayMore data for this Ligand-Target Pair