TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
Affinity DataKi: 0.470nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetEndothelin receptor type B(Homo sapiens (Human))
Banyu Pharmaceutical
Curated by PDSP Ki Database
Banyu Pharmaceutical
Curated by PDSP Ki Database
Affinity DataKi: 280nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.310nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.510nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.570nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.680nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nM EC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.820nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.860nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMAssay Description:Inhibitory activity of the compound against I-labeled ET-1 binding to Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.960nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.970nMAssay Description:Binding affinity to human neuropeptide Y5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity towards endothelin A receptor in porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair