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Found 60 with Last Name = 'hanquet' and Initial = 'g'
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234807(CHEMBL1738733)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50130404(CHEMBL3633687)
Affinity DataIC50:  8nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM6878(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3n ...)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of human CLK1 (148 to 484 residues) expressed in Escherichia coli BL21(DE3) preincubated for 10 mins followed by AFRREWSPGKEAKK substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234809(CHEMBL4103030)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CLK1 using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234808(CHEMBL4090007)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CLK1 (148 to 484 residues) expressed in Escherichia coli BL21(DE3) preincubated for 10 mins followed by AFRREWSPGKEAKK substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM5875(2-Anilino-5-aryloxazole 39 | N-[5-(Ethylsulfonyl)-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of VEGFR2 (unknown origin) using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM5875(2-Anilino-5-aryloxazole 39 | N-[5-(Ethylsulfonyl)-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of GST-tagged human recombinant VEGFR2 kinase expressed in Sf9 insect cells by radiometric protein kinase assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50234811(CHEMBL4086603)
Affinity DataIC50:  23nMAssay Description:Inhibition of VEGFR2 (unknown origin) using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM6878(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3n ...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human CLK3 (275 to 632 residues) expressed in Escherichia coli BL21(DE3) preincubated for 10 mins followed by substrate addition by pyr...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234812(CHEMBL4078755)
Affinity DataIC50:  30nMAssay Description:Inhibition of human CLK1 using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234807(CHEMBL1738733)
Affinity DataIC50:  37nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  39nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50:  40nMAssay Description:Inhibition of rat lens ALR2 using methylglyoxal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234810(CHEMBL4065167)
Affinity DataIC50:  40nMAssay Description:Inhibition of human CLK1 using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50:  42nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50130405(CHEMBL3633688)
Affinity DataIC50:  45nMAssay Description:Inhibition of His6-tagged KDR 789 to 1354 residues (unknown origin) using biotin-Ahx-AEEEYFFLA-amide substrate incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50130403(CHEMBL3633689)
Affinity DataIC50:  49nMAssay Description:Inhibition of GST-tagged human KDR expressed in Sf21 cells using 4:1 polyglutamic acid/tyrosine substrate incubated for 15 mins by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50:  51nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234808(CHEMBL4090007)
Affinity DataIC50:  55nMAssay Description:Inhibition of human DYRK1A preincubated for 10 mins followed by YRASPSRPESPRPPA-amide substrate addition by pyruvate kinase and lactate dehydrogenase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50:  66nMAssay Description:Inhibition of human AKR1B1 expressed in Escherichia coli using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234811(CHEMBL4086603)
Affinity DataIC50:  80nMAssay Description:Inhibition of human CLK1 using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519877(CHEMBL4462469)
Affinity DataIC50:  85nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50080464(ALR2 inhibitor, 12 | CHEMBL1405739)
Affinity DataIC50:  102nMAssay Description:Inhibition of human AKR1B1 expressed in Escherichia coli using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50080464(ALR2 inhibitor, 12 | CHEMBL1405739)
Affinity DataIC50:  116nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519877(CHEMBL4462469)
Affinity DataIC50:  118nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519875(CHEMBL4566195)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50080464(ALR2 inhibitor, 12 | CHEMBL1405739)
Affinity DataIC50:  146nMAssay Description:Inhibition of rat lens ALR2 using methylglyoxal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50080464(ALR2 inhibitor, 12 | CHEMBL1405739)
Affinity DataIC50:  176nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50363645(DEBROMOHYMENIALDISINE)
Affinity DataIC50:  183nMAssay Description:Inhibition of CHK2 (unknown origin) using polypeptide substrate after 40 mins in presence of [gamma-33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234810(CHEMBL4065167)
Affinity DataIC50:  200nMAssay Description:Inhibition of CDK9/CyclinT (unknown origin) using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM6878(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3n ...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human GSK3beta using Biotin-labeled GSP-2 peptide substrate after 90 mins in presence of [gamma33-P]ATP by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50:  216nMAssay Description:Inhibition of rat lens ALR2 using 4-hydroxynonenal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519875(CHEMBL4566195)
Affinity DataIC50:  233nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50:  292nMAssay Description:Inhibition of rat lens ALR2 using 4-hydroxynonenal glutathione as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519876(CHEMBL4541343)
Affinity DataIC50:  434nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234812(CHEMBL4078755)
Affinity DataIC50:  500nMAssay Description:Inhibition of DYRK1A (unknown origin) using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234808(CHEMBL4090007)
Affinity DataIC50:  530nMAssay Description:Inhibition of human CLK3 (275 to 632 residues) expressed in Escherichia coli BL21(DE3) preincubated for 10 mins followed by substrate addition by pyr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50080464(ALR2 inhibitor, 12 | CHEMBL1405739)
Affinity DataIC50:  644nMAssay Description:Inhibition of rat lens ALR2 using 4-hydroxynonenal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50363645(DEBROMOHYMENIALDISINE)
Affinity DataIC50:  725nMAssay Description:Inhibition of CHK1 (unknown origin) using polypeptide substrate after 40 mins in presence of [gamma-33P]ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519876(CHEMBL4541343)
Affinity DataIC50:  787nMAssay Description:Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234809(CHEMBL4103030)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Rattus norvegicus)
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50080464(ALR2 inhibitor, 12 | CHEMBL1405739)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of rat lens ALR2 using 4-hydroxynonenal glutathione as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50130408(CHEMBL3633692)
Affinity DataIC50:  6.96E+3nMAssay Description:Inhibition of GST-tagged human recombinant VEGFR2 kinase expressed in Sf9 insect cells by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234810(CHEMBL4065167)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50234810(CHEMBL4065167)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of GSK3 alpha/beta (unknown origin) using substrate after 30 mins in presence of [gamma-33P]ATP by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50130410(CHEMBL3633690)
Affinity DataIC50:  4.01E+4nMAssay Description:Inhibition of GST-tagged human recombinant VEGFR2 kinase expressed in Sf9 insect cells by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50130406(CHEMBL3633696)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of GST-tagged human recombinant VEGFR2 kinase expressed in Sf9 insect cells by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
Comenius University In Bratislava

Curated by ChEMBL
LigandPNGBDBM50519874(CHEMBL4582264)
Affinity DataIC50:  5.62E+4nMAssay Description:Inhibition of human AKR1B10 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50130409(CHEMBL3633691)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-tagged human recombinant VEGFR2 kinase expressed in Sf9 insect cells by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50130407(CHEMBL3633695)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GST-tagged human recombinant VEGFR2 kinase expressed in Sf9 insect cells by radiometric protein kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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