TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Binding affinity against LTD4 receptor in guinea pig lung membranes.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Binding affinity against LTD4 receptor in guinea pig lung membranes.More data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Antagonistic activity of the compound against LTB4 receptor using guinea pig (GP) spleen cell membraneMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:In vitro binding affinity against cysteinyl leukotriene D4 receptor from guinea pig lung membraneMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity against LTD4 receptor in guinea pig lung membranes.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity against LTD4 receptor in guinea pig lung membranes.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Binding affinity against PDE4 was determined using [3H]- rolipram in guinea pig brain membrane binding assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity at Phosphodiesterase 4 by measuring displacement of (+/-)-[3H]- Rolipram to guinea pig brain membranes.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Binding affinity against LTD4 receptor in guinea pig lung membranes.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity against LTD4 receptor in guinea pig lung membranes.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Binding affinity against LTD4 receptor in guinea pig lung membranes.More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity towards human opioid Mu receptor transfected into Chinese hamster ovary (CHO) cells using [3H]-DAMGO as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Antagonistic activity of the compound against monkey neutrophil LTB4 receptor 2 min after an iv dose of 3 mg/kg .More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.7kJ/molepH: 7.0 T: 2°CAssay Description:BChE inhibitions by the carbamate inhibitors were assayed by the Ellman method [Ellman et al., Biochem. Pharm., 7:88-95]. BChE-catalyzed hydrolysis o...More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Binding affinity against LTD4 receptor in guinea pig lung membranes.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity against LTD4 receptor in guinea pig lung membranes.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity against LTD4 receptor in guinea pig lung membranes.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University
Michigan State University
Affinity DataKi: 3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
Affinity DataKi: 3nM ΔG°: -48.6kJ/molepH: 7.0 T: 2°CAssay Description:BChE inhibitions by the carbamate inhibitors were assayed by the Ellman method [Ellman et al., Biochem. Pharm., 7:88-95]. BChE-catalyzed hydrolysis o...More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Binding affinity towards human opioid Mu receptor transfected into Chinese hamster ovary (CHO) cells using [3H]-DAMGO as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University
Michigan State University
Affinity DataKi: 4.10nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University
Michigan State University
Affinity DataKi: 4.10nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Affinity for phosphodiesterase (PDE IV) in guinea pig brain membrane using [3H]rolipram displacement.More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Inhibition of rolipram binding to Phosphodiesterase 4More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Affinity for rolipram binding site of phosphodiesterase type IV (PDE4)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Binding affinity against PDE4 was determined using [3H]- rolipram in guinea pig brain membrane binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -47.4kJ/molepH: 7.0 T: 2°CAssay Description:BChE inhibitions by the carbamate inhibitors were assayed by the Ellman method [Ellman et al., Biochem. Pharm., 7:88-95]. BChE-catalyzed hydrolysis o...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataKi: 5.30nMAssay Description:Binding affinity towards human opioid Mu receptor transfected into Chinese hamster ovary (CHO) cells using [3H]-DAMGO as radioligandMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 5.30nMAssay Description:Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Rhone-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Binding affinity against LTD4 receptor in guinea pig lung membranes.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University
Michigan State University
Affinity DataKi: 6.30nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Binding affinity towards human opioid Delta receptor transfected into Chinese hamster ovary (CHO) cells using [3H]-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Rh£Ne-Poulenc Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Binding affinity against PDE4 was determined using [3H]- rolipram in guinea pig brain membrane binding assayMore data for this Ligand-Target Pair