TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Inhibition of VEGFR2 by [32P]ATP-competitive radioassayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Inhibition of VEGFR2 by [32P]ATP-competitive radioassayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of VEGFR2 by [32P]ATP-competitive radioassayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERalpha expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERbeta expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged GPR30 expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetG-protein coupled estrogen receptor 1(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged GPR30 expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Inhibition of VEGFR2 (unknown origin) at IC90 concentration by ATP based competition assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Displacement of [32P]ATP from human VEGFR2 after 45 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Displacement of [32P]ATP from human VEGFR2 after 45 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Displacement of [32P]ATP from human VEGFR2 after 45 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Inhibition of VEGFR2 (unknown origin) at IC50 concentration by ATP based competition assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Inhibition of VEGFR2 (unknown origin) at IC90 concentration by ATP based competition assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Inhibition of VEGFR2 (unknown origin) at IC50 concentration by ATP based competition assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Inhibition of VEGFR2 (unknown origin) at IC90 concentration by ATP based competition assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Displacement of [32P]ATP from human VEGFR2 after 45 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Displacement of [32P]ATP from human VEGFR2 after 45 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Inhibition of VEGFR2 (unknown origin) at IC50 concentration by ATP based competition assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERalpha expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERalpha expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at human EP3 receptor assessed as cAMP production by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair