Compile Data Set for Download or QSAR
maximum 50k data
Found 226 with Last Name = 'lesnick' and Initial = 'jd'
LigandPNGBDBM50149477(CHEMBL3770993 | US10851091, U.S. Pat. No. 8,242,10...)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM81811(CAS_123679 | L-657,743 | MK-912 | NSC_123679)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408198(CHEMBL91278)
Affinity DataKi:  0.0794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50149482(CHEMBL3770709)
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50149553(CHEMBL3770306)
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.126nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50060964((R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-...)
Affinity DataKi:  0.126nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408201(CHEMBL88512)
Affinity DataKi:  0.126nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50149483(CHEMBL3770325)
Affinity DataKi:  0.200nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50149548(CHEMBL3771364 | US10851091, U.S. Pat. No. 8,242,10...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
LigandPNGBDBM50149554(CHEMBL3770140)
Affinity DataKi:  0.300nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50434806(2-(4-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-y...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
LigandPNGBDBM50149476(CHEMBL3770717)
Affinity DataKi:  0.300nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50019492((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
Affinity DataKi:  0.360nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408246(CHEMBL92261)
Affinity DataKi:  0.398nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408248(CHEMBL330060)
Affinity DataKi:  0.398nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50149465(CHEMBL3769854)
Affinity DataKi:  0.5nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50033112(6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyla...)
Affinity DataKi:  0.501nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  0.550nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(MOUSE)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50019492((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
Affinity DataKi:  0.620nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50019492((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
Affinity DataKi:  0.790nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50160165(CHEMBL88272 | RS-17053 | [2-(2-Cyclopropylmethoxy-...)
Affinity DataKi:  0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408244(CHEMBL93736)
Affinity DataKi:  0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408232(CHEMBL91093)
Affinity DataKi:  0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408242(CHEMBL91876)
Affinity DataKi:  0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM31046(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
Affinity DataKi:  0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408205(CHEMBL88435)
Affinity DataKi:  0.794nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408229(CHEMBL329160)
Affinity DataKi:  0.794nMAssay Description:The compound was screened in vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM81811(CAS_123679 | L-657,743 | MK-912 | NSC_123679)
Affinity DataKi:  0.850nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM81811(CAS_123679 | L-657,743 | MK-912 | NSC_123679)
Affinity DataKi:  0.890nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50149546(CHEMBL3769966)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50149545(CHEMBL3770824)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50149550(CHEMBL3770332)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
LigandPNGBDBM50398400(CHEMBL2178606)
Affinity DataKi:  1nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using dioctanoylglycerol-PIP2 as substrate incubated for 30 mins in presence of TAMRA-PIP3 by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50149543(CHEMBL3770630)
Affinity DataKi:  1.20nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50149479(CHEMBL3770092)
Affinity DataKi:  1.30nMAssay Description:Inhibition of recombinant PI3K alpha (unknown origin) using PIP2 as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408238(CHEMBL89916)
Affinity DataKi:  1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408192(CHEMBL90869)
Affinity DataKi:  1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408202(CHEMBL92901)
Affinity DataKi:  1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408208(CHEMBL88820)
Affinity DataKi:  1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408239(CHEMBL90874)
Affinity DataKi:  1.60nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50019492((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
Affinity DataKi:  1.62nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50408194(CHEMBL90287)
Affinity DataKi:  2nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177662(CHEMBL3813842)
Affinity DataKi:  2nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using dioctanoylglycerol-PIP2 as substrate incubated for 30 mins in presence of TAMRA-PIP3 by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177664(CHEMBL3814414)
Affinity DataKi:  2nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using dioctanoylglycerol-PIP2 as substrate incubated for 30 mins in presence of TAMRA-PIP3 by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398399(CHEMBL2178608)
Affinity DataKi:  2nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using dioctanoylglycerol-PIP2 as substrate incubated for 30 mins in presence of TAMRA-PIP3 by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Roche Bioscience

Curated by ChEMBL
LigandPNGBDBM50033111(1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...)
Affinity DataKi:  2.5nMAssay Description:In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50177669(CHEMBL3814544)
Affinity DataKi:  3nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using dioctanoylglycerol-PIP2 as substrate incubated for 30 mins in presence of TAMRA-PIP3 by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 226 total ) | Next | Last >>
Jump to: