TargetcAMP-dependent protein kinase(Oryctolagus cuniculus (Rabbit))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 0.0160nMAssay Description:Inhibition of cAMP dependent Protein kinase A of rabbit Skeletal Muscle.More data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of Smooth muscle myosin light chain kinase of chicken gizzardMore data for this Ligand-Target Pair
Affinity DataIC50: 0.177nMAssay Description:Inhibition of human MMP-9 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Binding activity to ET-B receptor on bovine cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.422nMAssay Description:Inhibition of human MMP-2 by fluorometric assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Ability to inhibit human trk A tyrosine kinase expressed in baculovirus using ELISA based enzyme assay was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Binding activity to ET-B receptor on bovine cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Binding activity to ET-B receptor on bovine cerebellum membraneMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
Affinity DataIC50: 4.35nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
Affinity DataIC50: 5.04nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 5.22nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Binding activity against Endothelin B receptor expressed from bovine cerebellum membrane preparationMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:Binding activity against Endothelin B receptor expressed from bovine cerebellum membrane preparationMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of Smooth muscle myosin light chain kinase of chicken gizzardMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Binding activity against Endothelin B receptor expressed from bovine cerebellum membrane preparationMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase(Oryctolagus cuniculus (Rabbit))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:Inhibition of cAMP dependent Protein kinase A of rabbit Skeletal Muscle.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Binding activity to ET-B receptor on bovine cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Binding activity against Endothelin B receptor expressed from bovine cerebellum membrane preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 12.4nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 14.8nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human MMP-3 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15.2nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human MMP-2 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18.6nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 18.8nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Displacement of (S)-N-(2-(N-(3-biphenyl-4-ylcarboxamido-4-(hydroxyamino)-4-oxobutyl)sulfamoyl)ethyl)-3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9...More data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
Affinity DataIC50: 23.7nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 24.6nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Displacement of (S)-N-(2-(N-(3-biphenyl-4-ylcarboxamido-4-(hydroxyamino)-4-oxobutyl)sulfamoyl)ethyl)-3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9...More data for this Ligand-Target Pair
Affinity DataIC50: 27.8nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 28.4nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 30.1nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 32.3nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 32.7nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Binding activity against Endothelin B receptor expressed from bovine cerebellum membrane preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 36.1nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 36.4nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 37.3nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Binding activity against Endothelin B receptor expressed from bovine cerebellum membrane preparationMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
Affinity DataIC50: 49.7nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair
Affinity DataIC50: 50.6nMAssay Description:CHO cells stably expressing human metabotropic glutamate receptors mGluR2 and mGluR3 were cultured at 37° C. under 5% CO2 using a Dulbecco's modi...More data for this Ligand-Target Pair