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Found 121 with Last Name = 'mcgovern' and Initial = 'r'
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109179(4-[3-(3-{3-[4-(3-Hydroxy-phenyl)-piperidin-1-yl]-p...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109122(4-[3-(3-{3-[4-(3-Methoxy-phenyl)-piperidin-1-yl]-p...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109188(4-[3-(3-{3-[4-(2-Methoxy-phenyl)-piperidin-1-yl]-p...)
Affinity DataKi:  4.10nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109182(4-(3-{3-[3-(4-Cyclohexyl-piperidin-1-yl)-propyl]-u...)
Affinity DataKi:  9.5nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109186(2,6-Dimethyl-4-(3-{3-[3-(4-phenyl-piperidin-1-yl)-...)
Affinity DataKi:  10nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109185(4-[3-(3-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-p...)
Affinity DataKi:  12nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50060728((R)-2-(2,2-diphenylacetamido)-5-guanidino-N-(4-hyd...)
Affinity DataKi:  15nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109194(4-[3-(3-{3-[4-(3-Hydroxy-phenyl)-piperazin-1-yl]-p...)
Affinity DataKi:  37nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109173(2,6-Dimethyl-4-(3-{3-[3-(4-phenyl-piperazin-1-yl)-...)
Affinity DataKi:  66nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109193(4-(3-{3-[3-(4-Benzyl-piperidin-1-yl)-propyl]-ureid...)
Affinity DataKi:  84nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109178(2,6-Dimethyl-4-(3-{3-[3-(4-phenyl-piperidin-1-yl)-...)
Affinity DataKi:  89nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109183(2,6-Dimethyl-4-(3-{3-[3-(4-o-tolyl-piperazin-1-yl)...)
Affinity DataKi:  96nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109192(4-[3-(3-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-p...)
Affinity DataKi:  105nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109180(4-[3-(3-{3-[4-(2-Hydroxy-phenyl)-piperazin-1-yl]-p...)
Affinity DataKi:  108nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109181(4-(3-{3-[3-(4-Biphenyl-3-yl-piperidin-1-yl)-propyl...)
Affinity DataKi:  188nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109190(4-[3-(3-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-pr...)
Affinity DataKi:  322nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109177(4-[3-(3-{3-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-p...)
Affinity DataKi:  405nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109184(2,6-Dimethyl-4-(3-{3-[3-(4-p-tolyl-piperazin-1-yl)...)
Affinity DataKi:  503nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109176(2,6-Dimethyl-4-{3-[3-(3-piperidin-1-yl-propyl)-ure...)
Affinity DataKi:  523nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109189(4-[3-(3-{3-[4-(3,4-Dichloro-phenyl)-piperazin-1-yl...)
Affinity DataKi:  677nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109191(5-Cyano-4-[3-(3-{3-[4-(2-methoxy-phenyl)-piperazin...)
Affinity DataKi:  684nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109175(4-[3-(3-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-p...)
Affinity DataKi:  995nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109174(2,6-Dimethyl-4-{3-[3-(3-piperazin-1-yl-propyl)-ure...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50109187(4-[3-(3-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-p...)
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of binding of [125I]-PYY radioligand to human neuropeptide Y1 receptor in SK-N-MC cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50240412(3-(4-{7-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexen...)
Affinity DataIC50:  0.0500nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285314(3-(4-{8-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexen...)
Affinity DataIC50:  0.110nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50285320(3-(4-{12-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexe...)
Affinity DataIC50:  0.130nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50285313(3-(4-{10-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexe...)
Affinity DataIC50:  0.220nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285320(3-(4-{12-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexe...)
Affinity DataIC50:  0.330nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50122418(1-Benzo[1,3]dioxol-5-yl-4-[4-(2-fluoro-5-methoxy-b...)
Affinity DataIC50:  0.75nMAssay Description:Inhibition of the 5-hydroxytryptamine 1A receptor in rat dorsal rapheMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285316(3-(4-{6-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexen...)
Affinity DataIC50:  0.830nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50122426(1-Benzo[1,3]dioxol-5-yl-4-[4-(2-bromo-benzyl)-pipe...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of the 5-hydroxytryptamine 1A receptor in rat dorsal rapheMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50122429(1-Benzo[1,3]dioxol-5-yl-4-[4-(2-iodo-benzyl)-piper...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of the 5-hydroxytryptamine 1A receptor in rat dorsal rapheMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50285319(3-(4-Heptylamino-cyclohex-1-enyl)-1H-indole-5-carb...)
Affinity DataIC50:  1.27nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50240412(3-(4-{7-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexen...)
Affinity DataIC50:  1.83nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50122428(1-Benzo[1,3]dioxol-5-yl-4-[4-(2-chloro-benzyl)-pip...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of the 5-hydroxytryptamine 1A receptor in rat dorsal rapheMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285319(3-(4-Heptylamino-cyclohex-1-enyl)-1H-indole-5-carb...)
Affinity DataIC50:  1.98nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50285315(3-(4-{2-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexen...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50285314(3-(4-{8-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexen...)
Affinity DataIC50:  2.13nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50122411(1-Benzo[1,3]dioxol-5-yl-4-[4-(3-methoxy-benzyl)-pi...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of the 5-hydroxytryptamine 1A receptor in rat dorsal rapheMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50285316(3-(4-{6-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexen...)
Affinity DataIC50:  2.27nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50122437(1-Benzo[1,3]dioxol-5-yl-4-[4-(2,5-difluoro-benzyl)...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of the 5-hydroxytryptamine 1A receptor in rat dorsal rapheMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285313(3-(4-{10-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexe...)
Affinity DataIC50:  2.63nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50122433(1-Benzo[1,3]dioxol-5-yl-4-[4-(3-bromo-benzyl)-pipe...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of the 5-hydroxytryptamine 1A receptor in rat dorsal rapheMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50285318(3-(4-{5-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexen...)
Affinity DataIC50:  2.86nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1A receptor receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285318(3-(4-{5-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexen...)
Affinity DataIC50:  3.35nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50122431(1-Benzo[1,3]dioxol-5-yl-4-[4-(3-chloro-benzyl)-pip...)
Affinity DataIC50:  6nMAssay Description:Inhibition of the 5-hydroxytryptamine 1A receptor in rat dorsal rapheMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50122423(1-Benzo[1,3]dioxol-5-yl-4-[4-(3-ethoxy-benzyl)-pip...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of the 5-hydroxytryptamine 1A receptor in rat dorsal rapheMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50285315(3-(4-{2-[4-(5-carbamoyl-1H-3-indolyl)-3-cyclohexen...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50122410(1-Benzo[1,3]dioxol-5-yl-4-[4-(2-fluoro-benzyl)-pip...)
Affinity DataIC50:  10nMAssay Description:Inhibition of the 5-hydroxytryptamine 1A receptor in rat dorsal rapheMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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