Compile Data Set for Download or QSAR
maximum 50k data
Found 3805 with Last Name = 'miller' and Initial = 'k'
TargetNicotinic acetylcholine receptor(RAT)
University Of Kentucky

Curated by PDSP Ki Database
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)
Affinity DataKi:  0.0800nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125155(1-(2-Amino-4-fluoro-phenyl)-4-(6bR,10aS)-1,2,6b,9,...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125161(1-(2-Amino-4-fluoro-phenyl)-4-(6bR,10aS)-1,2,6b,9,...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217586(CHEMBL442080 | N-(4-(3-((methylamino)methyl)-4-(4-...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217575(4-(4-(3-((methylamino)methyl)-4-(4-(methylthio)phe...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125173(1-(2-Amino-4-fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,1...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50371662(CHEMBL269974)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217584((5-(4-(4-isopropylpiperazin-1-yl)butyl)-2-(4-(meth...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217592((5-(4-(4-isopropylpiperazin-1-yl)but-1-ynyl)-2-(4-...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125154(1-(2-Amino-4-fluoro-phenyl)-4-(7aS,11aR)-5,6,8,9,1...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371305(CHEMBL272077)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217593((5-bromo-2-(4-(methylthio)phenoxy)phenyl)-N-methyl...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50200636(1-(4-(4-(piperidin-1-ylmethyl)phenyl)but-3-ynyl)pi...)
Affinity DataKi:  0.513nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50414797(CHEMBL582977)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125174(1-(2-Amino-phenyl)-4-(7bS,11aR)-6,7,8,9,11,11a-hex...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Vertex Pharmaceuticals

LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  0.600nM ΔG°:  -52.1kJ/molepH: 7.5 T: 2°CAssay Description:The kinase activity was determined by incubation of enzyme and its substrate, and test compound, in the presence ATP/[gamma-32P] ATP. After incubatio...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125170(1-(2-Amino-4-fluoro-phenyl)-4-(7bS,11aR)-4,5,6,7,8...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50159110(1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217579((5-(4-(4-fluoropiperidin-1-yl)but-1-ynyl)-2-(4-(me...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217590((5-(4-(4-cyclopropylpiperazin-1-yl)butyl)-2-(4-(me...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50371682(CHEMBL270188)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50414804(CHEMBL574712)
Affinity DataKi:  0.617nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinic acetylcholine receptor(RAT)
University Of Kentucky

Curated by PDSP Ki Database
LigandPNGBDBM50054820(Methyllycaconitine | [(1S,4S,5R,6S,8R,9R,13S,16S,1...)
Affinity DataKi:  0.640nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50414811(CHEMBL574721)
Affinity DataKi:  0.676nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125173(1-(2-Amino-4-fluoro-phenyl)-4-(7bS,11aR)-6,7,8,9,1...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity towards DA D2 receptor using [3H]-N-methyl-spiperone as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217565((5-(4-(4-isopropyl-1,4-diazepan-1-yl)but-1-ynyl)-2...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217589((6S,10bR)-6-(4-methoxyphenyl)-9-(3-(piperidin-1-yl...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371294(CHEMBL257208)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217572(CHEMBL393036 | N-methyl(2-(4-(methylthio)phenoxy)-...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217589((6S,10bR)-6-(4-methoxyphenyl)-9-(3-(piperidin-1-yl...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50371669(CHEMBL402164)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125163(1-(2-Amino-phenyl)-4-(7bS,11aR)-4,5,6,7,8,9,11,11a...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217572(CHEMBL393036 | N-methyl(2-(4-(methylthio)phenoxy)-...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209802(CHEMBL438490 | N,N-dimethyl-3-phenoxy-3-(4-(3-(pip...)
Affinity DataKi:  0.720nMAssay Description:Binding affinity at human histamine H3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50414798(CHEMBL575172)
Affinity DataKi:  0.724nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]BMS-725519 from human CB1 receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50414800(CHEMBL583182)
Affinity DataKi:  0.759nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50414792(CHEMBL573817)
Affinity DataKi:  0.776nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217576(CHEMBL236046 | N-methyl(2-(4-(methylthio)phenoxy)-...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125177(CHEMBL162768 | N-[5-Fluoro-2-((7bS,11aR)-4-6,7,8,9...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125169(1-(2-Amino-phenyl)-4-(6bR,10aS)-1,2,6b,9,10,10a-he...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371289(CHEMBL258349)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371290(CHEMBL401683)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50125151(1-(2-Amino-phenyl)-4-(7aS,11aR)-5,6,8,9,11,11a-hex...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [125I]-DOI as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217576(CHEMBL236046 | N-methyl(2-(4-(methylthio)phenoxy)-...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50371681(CHEMBL271418)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50414813(CHEMBL573328)
Affinity DataKi:  0.871nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50414799(CHEMBL573815)
Affinity DataKi:  0.891nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217579((5-(4-(4-fluoropiperidin-1-yl)but-1-ynyl)-2-(4-(me...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50217577(CHEMBL236010 | N-methyl(2-(4-(methylthio)phenoxy)-...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 3805 total ) | Next | Last >>
Jump to: