Found 1826 with Last Name = 'mol' and Initial = 'f' TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.0400nMAssay Description:Binding inhibition towards human serotonin transporterMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 0.0750nMAssay Description:The binding affinity of the compound was measured on histamine H1 receptor using [3H]- mepyramine as radioligand.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:In vitro binding inhibition towards human serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:The binding affinity of the compound was measured on alpha2-adrenergic receptor using [3H]- clonidine as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:The binding affinity was measured on 5-hydroxytryptamine 3 receptor using [3H]GR-65630 as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Displacement of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:The binding affinity of the compound was measured on glycine receptor using [3H]- strychnine as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:The binding affinity of the compound was measured on muscarine M1 receptor using [3H]- pirenzepine as radioligand.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.560nMAssay Description:Binding inhibition towards human serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.580nMAssay Description:Binding inhibition towards human serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:The binding affinity of the compound was measured on dopamine receptor D1 using [3H]- dopamine as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:The binding affinity of the compound was measured on 5-hydroxytryptamine 1C receptor using [3H]- serotonin as radioligand.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.720nMAssay Description:Binding inhibition towards human serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.770nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.780nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:The binding affinity of the compound was measured on kappa-opiate receptor using [3H]- EKC as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:The binding affinity of the compound was measured on 5-hydroxytryptamine 3 receptor using [3H]- GR-65,630 as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:The binding affinity of the compound was measured on mu-opiate receptor using [3H]- naloxone as radioligand.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataKi: 1.20nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataKi: 1.20nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataKi: 1.40nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:The binding affinity was measured on muscarine M2 receptor using [3H]- N-Me-SCOPOL as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:The binding affinity of the compound was measured on imidazoline I2 receptor using [3H]- indazoxan as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity to CRFR1 by autoradiographyMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity to CRFR1 by autoradiographyMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity to CRFR1 by autoradiographyMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Binding inhibition towards human serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataKi: 2nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding inhibition towards human serotonin transporterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity to CRFR1 by autoradiographyMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataKi: 2nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Binding inhibition towards human serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Binding inhibition towards human serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 2.20nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 2.20nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataKi: 2.40nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataKi: 2.60nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Albany Molecular Research
US Patent
Albany Molecular Research
US Patent
Affinity DataKi: <3nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: <3nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 3.30nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 3.40nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 3.40nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
Affinity DataKi: 3.80nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
