Compile Data Set for Download or QSAR
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Found 454 with Last Name = 'moore' and Initial = 'f'
TargetMelanin-concentrating hormone receptor 1(RAT)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50241083(6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1...)
Affinity DataKi:  0.340nMAssay Description:Antagonist activity at rat MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50094880(CHEMBL3589145)
Affinity DataKi:  0.800nMAssay Description:Antagonist activity at rat MCHR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Newt)
Oregon State University

Curated by PDSP Ki Database
LigandPNGBDBM21244(2-[(1S,2S,5S)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataKi:  3.80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(RAT)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50094885(CHEMBL3588863)
Affinity DataKi:  3.80nMAssay Description:Antagonist activity at rat MCHR1 assessed as 2-(4-chlorophenyl)-5-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50262988(CHEMBL1200541 | N-(2-chlorobenzyl)-2-(2-(2-((2-chl...)
Affinity DataKi:  5nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50262988(CHEMBL1200541 | N-(2-chlorobenzyl)-2-(2-(2-((2-chl...)
Affinity DataKi:  6nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelanin-concentrating hormone receptor 1(RAT)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50094881(CHEMBL3589155)
Affinity DataKi:  7.20nMAssay Description:Antagonist activity at rat MCHR1 assessed as 6-(4-chlorophenyl)-3-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)thieno[3,2-d]pyrimidin-4(3H)-oneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  10nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor complexMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Newt)
Oregon State University

Curated by PDSP Ki Database
LigandPNGBDBM84888(CAS_107822 | CAS_71048-87-8 | Levonantradol | NSC_...)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Newt)
Oregon State University

Curated by PDSP Ki Database
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  25.7nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50119797(1,1'-(decane-1,10-diyl)diquinolinium iodide | 1,10...)
Affinity DataKi:  40nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  50nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complexMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50119797(1,1'-(decane-1,10-diyl)diquinolinium iodide | 1,10...)
Affinity DataKi:  60nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM120262(EDROPHONIUM BROMIDE | EDROPHONIUM CHLORIDE | Edrop...)
Affinity DataKi:  800nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50339942(1,1'-(naphthalene-2,7-diylbis(methylene))diquinoli...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Newt)
Oregon State University

Curated by PDSP Ki Database
LigandPNGBDBM85675(Anandamide + PMSF | CHEMBL321585)
Affinity DataKi:  2.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM120262(EDROPHONIUM BROMIDE | EDROPHONIUM CHLORIDE | Edrop...)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50339942(1,1'-(naphthalene-2,7-diylbis(methylene))diquinoli...)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM8958(10-(2-diethylaminopropyl)phenothiazine | CHEMBL120...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM8958(10-(2-diethylaminopropyl)phenothiazine | CHEMBL120...)
Affinity DataKi:  1.21E+7nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStanniocalcin-1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM201239(US9187424, 6-2)
Affinity DataIC50:  0.580nMAssay Description:Inhibition of mouse STC1 in cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStanniocalcin-1(Homo sapiens)
TBA

Curated by ChEMBL
LigandPNGBDBM201239(US9187424, 6-2)
Affinity DataIC50:  0.630nMAssay Description:Inhibition of human STC1 in cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50262988(CHEMBL1200541 | N-(2-chlorobenzyl)-2-(2-(2-((2-chl...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human erythrocyte recombinant AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Charles University

Curated by ChEMBL
LigandPNGBDBM50119797(1,1'-(decane-1,10-diyl)diquinolinium iodide | 1,10...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human erythrocyte recombinant AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50229040(CHEMBL156140)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50579517(CHEMBL4847167)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579517(CHEMBL4847167)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in Sf9 cell membrane using 2-oleoylglycerol and oleoyl-CoA as substrates incubated for 10 mins by LCM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM201239(US9187424, 6-2)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM201301(US9187424, 65 | US9187424, 77)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50229041(CHEMBL351567)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50579522(CHEMBL4863471)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579531(CHEMBL4869563)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM201239(US9187424, 6-2)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of rat recombinant MGAT2 expressed in Sf9 cell membrane using 2-oleoylglycerol and oleoyl-CoA as substrates incubated for 10 mins by LCMS ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50229038(CHEMBL345917)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM201316(US9187424, 145 | US9187424, 80)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in Sf9 cell membrane using 2-oleoylglycerol and oleoyl-CoA as substrates incubated for 10 mins by LCM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM201295(US9187424, 59)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579508(CHEMBL4868038)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579529(CHEMBL4875367)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579511(CHEMBL4872250)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579511(CHEMBL4872250)
Affinity DataIC50:  5nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in Sf9 cell membrane using 2-oleoylglycerol and oleoyl-CoA as substrates incubated for 10 mins by LCM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579522(CHEMBL4863471)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in Sf9 cell membrane using 2-oleoylglycerol and oleoyl-CoA as substrates incubated for 10 mins by LCM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579514(CHEMBL4863703)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM201316(US9187424, 145 | US9187424, 80)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579520(CHEMBL4851952)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579509(CHEMBL4872517)
Affinity DataIC50:  6nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in Sf9 cell membrane using 2-oleoylglycerol and oleoyl-CoA as substrates incubated for 10 mins by LCM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579526(CHEMBL4878564)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50579531(CHEMBL4869563)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of mouse recombinant MGAT2 expressed in Sf9 cell membrane using 2-oleoylglycerol and oleoyl-CoA as substrates incubated for 10 mins by LCM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50442178(CHEMBL2441600 | US9187424, 124)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50579510(CHEMBL4865613)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of human recombinant MGAT2 expressed in Sf9 cell membrane using 2-monooleglycerol and [H3]-oleoyl-CoA as substrates incubated for 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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