TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.00700nMAssay Description:Binding affinity of the compound towards HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.00700nM ΔG°: -63.0kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 0.00800nM ΔG°: -62.7kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.0180nMAssay Description:Binding affinity of the compound towards HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0180nM ΔG°: -60.7kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 0.0320nM ΔG°: -59.3kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nM ΔG°: -58.8kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.0500nMAssay Description:Binding affinity of the compound towards HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nM ΔG°: -57.8kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.0650nMAssay Description:Binding affinity of the compound towards HIV protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.0750nMAssay Description:Binding affinity of the compound towards HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nM ΔG°: -56.5kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nM ΔG°: -57.5kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nM ΔG°: -56.5kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Compound was evaluated for in vitro inhibition of human immunodeficiency virus type 1 (HIV-1) ProteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Compound was evaluated for in vitro inhibition of human immunodeficiency virus type 1 (HIV-1) ProteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nM ΔG°: -56.1kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 0.120nM ΔG°: -56.1kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.147nMAssay Description:Binding affinity of the compound towards HIV protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.175nMAssay Description:Binding affinity of the compound towards HIV protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Binding affinity of the compound towards HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nM ΔG°: -54.8kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity of the compound towards HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nM ΔG°: -54.6kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Binding affinity of the compound towards HIV protease was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -53.8kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -54.7kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
Affinity DataKi: 0.480nM ΔG°: -52.7kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 0.520nM ΔG°: -52.5kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 0.540nM ΔG°: -52.4kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.660nMAssay Description:Inhibition of HIV-1 protease.More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of Mcl1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -51.7kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -52.6kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
Affinity DataKi: 0.710nM ΔG°: -51.7kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.730nMAssay Description:Inhibition of HIV-1 protease.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Inhibition of HIV-1 protease.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 0.860nMAssay Description:Inhibition of HIV-1 protease.More data for this Ligand-Target Pair
Affinity DataKi: 0.870nM ΔG°: -51.2kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 0.880nM ΔG°: -51.2kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -52.0kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
Affinity DataKi: 0.970nM ΔG°: -50.9kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Compound was evaluated for in vitro inhibition of human immunodeficiency virus type 1 (HIV-1) ProteaseMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Compound was evaluated for in vitro inhibition of human immunodeficiency virus type 1 (HIV-1) ProteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Pharmacia And Upjohn
Curated by ChEMBL
Pharmacia And Upjohn
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Antagonism against bradykinin receptor B2 in guinea pig ileal tissueMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair