TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
Affinity DataKi: 117nMAssay Description:Mixed non-competitive inhibition of HIV1 reverse transcriptase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of HIV1 reverse transcriptase activity by primer extension assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 21.5nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Pfizer
Pfizer
Affinity DataIC50: 32nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 39.7nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Pfizer
Pfizer
Affinity DataIC50: 40nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Pfizer
Pfizer
Affinity DataIC50: 61nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Pfizer
Pfizer
Affinity DataIC50: 68nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 112nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of HIV1 reverse transcriptase activity by primer extension assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Pfizer
Pfizer
Affinity DataIC50: 145nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Pfizer
Pfizer
Affinity DataIC50: 183nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 215nMAssay Description:Inhibition of HIV1 HXB2 reverse transcriptase K103N mutant activity by primer extension assayMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 332nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Pfizer
Pfizer
Affinity DataIC50: 364nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Pfizer
Pfizer
Affinity DataIC50: 384nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 399nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 414nMAssay Description:Inhibition of HIV1 HXB2 reverse transcriptase K103N mutant activity by primer extension assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Pfizer
Pfizer
Affinity DataIC50: 1.27E+3nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+3nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 9.80E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 3.90E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 624nMAssay Description:Binding affinity to recombinant HIV1 reverse transcriptase by isothermal calorimetryMore data for this Ligand-Target Pair