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Found 115 with Last Name = 'stammen' and Initial = 'bl'
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257637(1-(4-aminopyridin-2-yl)-4-phenyl-N-(quinolin-2-yl)...)
Affinity DataKi:  17nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257723(2-(3-phenyl-3H-spiro[isobenzofuran-1,4'-piperidine...)
Affinity DataKi:  18nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257639((1-(4-aminopyridin-2-yl)-4-phenylpiperidin-4-yl)(3...)
Affinity DataKi:  35nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400788(CHEMBL2203612)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257684(CHEMBL495346 | N-(1-(4-aminopyridin-2-yl)-4-phenyl...)
Affinity DataKi:  82nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257638(CHEMBL493743 | ethyl 4-(1-(4-aminopyridin-2-yl)-4-...)
Affinity DataKi:  169nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257683(1-(4-aminopyridin-2-yl)-N-(4-methoxybenzyl)-4-phen...)
Affinity DataKi:  201nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257685(CHEMBL492330 | N-(1-(4-aminopyridin-2-yl)-4-phenyl...)
Affinity DataKi:  343nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257833(3-(1-(4-aminopyridin-2-yl)piperidin-4-yl)-1-benzyl...)
Affinity DataKi:  518nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257686(CHEMBL522317 | N-(1-(4-aminopyridin-2-yl)-4-phenyl...)
Affinity DataKi:  548nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257834(3-(1-(4-aminopyridin-2-yl)piperidin-4-yl)-1-(cyclo...)
Affinity DataKi:  746nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257831(3-(1-(4-aminopyridin-2-yl)piperidin-4-yl)-1-(4-met...)
Affinity DataKi:  865nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257832(3-(1-(4-aminopyridin-2-yl)piperidin-4-yl)-1-phenyl...)
Affinity DataKi:  903nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257781(2-(3-(3-methoxyphenyl)-3-methylazetidin-1-yl)pyrid...)
Affinity DataKi:  1.84E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257780((S)-1'-(4-aminopyridin-2-yl)-N,N-dimethyl-2,3-dihy...)
Affinity DataKi:  4.71E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257782(CHEMBL493515 | N-(1-(4-aminopyridin-2-yl)piperidin...)
Affinity DataKi:  5.03E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257784(CHEMBL493517 | N-(1-(4-aminopyridin-2-yl)piperidin...)
Affinity DataKi:  9.69E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257783(CHEMBL493516 | N-(1-(4-aminopyridin-2-yl)piperidin...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257830(CHEMBL493781 | N-(1-(4-aminopyridin-2-yl)piperidin...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257719((S)-N-(1-(4-aminopyridin-2-yl)-4-phenylpiperidin-4...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50257722((S)-1'-(4-aminopyridin-2-yl)-N,N-diethyl-3H-spiro[...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50189399((S)-N-(3-(4-(2-(4-fluorophenyl)acetamido)piperidin...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400791(CHEMBL2203619)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50189401(CHEMBL214818 | N-((S)-3-(3-(2-methyl-1H-benzo[d]im...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400795(CHEMBL2203615)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50189394((S)-N-(3-(4-(3-benzyl-1H-1,2,4-triazol-1-yl)piperi...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50189400(CHEMBL213914 | N-[(1S)-3-[2'-(2-methyl-1H-1,3-benz...)
Affinity DataIC50:  6nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400794(CHEMBL2203616)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400787(CHEMBL2203613)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400788(CHEMBL2203612)
Affinity DataIC50:  9nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400792(CHEMBL2203618)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400796(CHEMBL2203614)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50189397((S)-N-(3-(4-(5-benzyl-1,2,4-oxadiazol-3-yl)piperid...)
Affinity DataIC50:  20nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400790(CHEMBL2203620)
Affinity DataIC50:  21.5nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50189395(CHEMBL413501 | N-((S)-3-(7-(2-methyl-1H-benzo[d]im...)
Affinity DataIC50:  39nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400789(CHEMBL2203621)
Affinity DataIC50:  39.7nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50189393((S)-N-(3-(4-(3,5-dimethyl-4H-1,2,4-triazol-4-yl)pi...)
Affinity DataIC50:  50nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50189396((S)-N-(3-(4-(5-methyl-1,2,4-oxadiazol-3-yl)piperid...)
Affinity DataIC50:  70nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095314(CHEMBL3589893)
Affinity DataIC50:  160nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095310(CHEMBL3589894)
Affinity DataIC50:  190nMAssay Description:Inhibition of human Nav1.8/beta1 expressed in HEK293 cells by manual patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095311(CHEMBL3589904)
Affinity DataIC50:  190nMAssay Description:Inhibition of human Nav1.8/beta1 expressed in HEK293 cells by manual patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50189398((S)-N-(3-(4-(3-benzyl-5-methyl-4H-1,2,4-triazol-4-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of [125I]MIP-1beta binding to CCR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095312(CHEMBL2324355)
Affinity DataIC50:  260nMAssay Description:Inhibition of human Nav1.8/beta1 expressed in HEK293 cells by manual patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095331(CHEMBL3589903)
Affinity DataIC50:  500nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095312(CHEMBL2324355)
Affinity DataIC50:  530nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095329(CHEMBL3589901)
Affinity DataIC50:  670nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095311(CHEMBL3589904)
Affinity DataIC50:  700nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095328(CHEMBL3589900)
Affinity DataIC50:  750nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50095330(CHEMBL3589902)
Affinity DataIC50:  920nMAssay Description:Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50400793(CHEMBL2203617)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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