Compile Data Set for Download or QSAR
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Found 52 with Last Name = 'sturdy' and Initial = 'm'
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29227(casimiroin analogue, 1p)
Affinity DataIC50:  100nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  270nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29229(casimiroin analogue, 1r)
Affinity DataIC50:  760nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  960nMAssay Description:Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) assessed as N-methyldihydronicotinamide oxidation per mg of protein a...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  960nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29221(casimiroin analogue, 1j)
Affinity DataIC50:  960nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29223(casimiroin analogue, 1l)
Affinity DataIC50:  960nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29213(casimiroin analogue, 1b)
Affinity DataIC50:  1.25E+3nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29221(casimiroin analogue, 1j)
Affinity DataIC50:  1.90E+3nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29217(casimiroin analogue, 1f)
Affinity DataIC50:  2.02E+3nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29225(casimiroin analogue, 1n)
Affinity DataIC50:  2.72E+3nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM50339150(5,7-dihydroxy-2-(4-hydroxyphenyl)-3-((2R,3S,4S,5S,...)
Affinity DataIC50:  3.84E+3nMAssay Description:Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) assessed as N-methyldihydronicotinamide oxidation per mg of protein a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29210(casimiroin)
Affinity DataIC50:  3.92E+3nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29223(casimiroin analogue, 1l)
Affinity DataIC50:  4.10E+3nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29228(casimiroin analogue, 1q)
Affinity DataIC50:  5.68E+3nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29219(casimiroin analogue, 1h)
Affinity DataIC50:  5.76E+3nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29217(casimiroin analogue, 1f)
Affinity DataIC50:  5.80E+3nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29226(casimiroin analogue, 1o)
Affinity DataIC50:  6.00E+3nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29213(casimiroin analogue, 1b)
Affinity DataIC50:  6.20E+3nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29225(casimiroin analogue, 1n)
Affinity DataIC50:  7.00E+3nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29220(casimiroin analogue, 1i)
Affinity DataIC50:  8.80E+3nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29219(casimiroin analogue, 1h)
Affinity DataIC50:  9.30E+3nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29224(casimiroin analogue, 1m)
Affinity DataIC50:  1.00E+4nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29227(casimiroin analogue, 1p)
Affinity DataIC50:  1.08E+4nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29222(casimiroin analogue, 1k)
Affinity DataIC50:  1.08E+4nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29212(casimiroin analogue, 1a)
Affinity DataIC50:  1.08E+4nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataIC50:  1.13E+4nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29226(casimiroin analogue, 1o)
Affinity DataIC50:  1.48E+4nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29215(casimiroin analogue, 1d)
Affinity DataIC50:  1.82E+4nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29224(casimiroin analogue, 1m)
Affinity DataIC50:  1.85E+4nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29216(casimiroin analogue, 1e)
Affinity DataIC50:  2.41E+4nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29222(casimiroin analogue, 1k)
Affinity DataIC50:  2.68E+4nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM50339149(CHEMBL1689259 | beta-(3,4-dihydroxyphenyl)ethyl-3-...)
Affinity DataIC50:  2.68E+4nMAssay Description:Inhibition of aromatase preincubated with 2.6 mM NADP+ for 10 mins before substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29218(casimiroin analogue, 1g)
Affinity DataIC50:  2.93E+4nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM50339147(CHEMBL1689257 | beta-(4-hydroxyphenyl)ethyl-4-O-E-...)
Affinity DataIC50:  3.07E+4nMAssay Description:Inhibition of aromatase preincubated with 2.6 mM NADP+ for 10 mins before substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29218(casimiroin analogue, 1g)
Affinity DataIC50:  3.15E+4nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM50339148(CHEMBL1689258 | beta-(3,4-dihydroxyphenyl)ethyl-6-...)
Affinity DataIC50:  3.23E+4nMAssay Description:Inhibition of aromatase preincubated with 2.6 mM NADP+ for 10 mins before substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM50269516(CHEMBL518414 | Calceolarioside B)
Affinity DataIC50:  3.53E+4nMAssay Description:Inhibition of aromatase preincubated with 2.6 mM NADP+ for 10 mins before substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29210(casimiroin)
Affinity DataIC50:  5.41E+4nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29220(casimiroin analogue, 1i)
Affinity DataIC50: >9.13E+4nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29230(quinone, 12)
Affinity DataIC50: >9.84E+4nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29212(casimiroin analogue, 1a)
Affinity DataIC50: >9.85E+4nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29216(casimiroin analogue, 1e)
Affinity DataIC50: >1.06E+5nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29215(casimiroin analogue, 1d)
Affinity DataIC50: >1.16E+5nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Purdue University

LigandPNGBDBM29214(casimiroin analogue, 1c | cid_69088)
Affinity DataIC50: >1.26E+5nMAssay Description:Aromatase inhibition was quantified by measuring the fluorescent intensity of fluorescein, the hydrolysis product of dibenzylfluorescein (DBF), by ar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29230(quinone, 12)
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29229(casimiroin analogue, 1r)
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29228(casimiroin analogue, 1q)
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosyldihydronicotinamide dehydrogenase [quinone](Homo sapiens (Human))
Yunnan Normal University

Curated by ChEMBL
LigandPNGBDBM29214(casimiroin analogue, 1c | cid_69088)
Affinity DataIC50: >5.00E+5nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50478130(CHEMBL271159)
Affinity DataEC50:  6.00E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 transcriptional activation in human U251-HRE cells by luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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