Compile Data Set for Download or QSAR
maximum 50k data
Found 45 with Last Name = 'sydor' and Initial = 'jr'
TargetSmoothened homolog(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293788(CHEMBL538867 | N-((2S,3R,3aS,3'R,4a'R,6S,6a'R,6b'S...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant SMO expressed in mouse C3H10T1/2 cells assessed as inhibition of association of BODIPY-cyclopamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191364(17-((S)-amino-3,2-propanediol)-17-demethoxygeldana...)
Affinity DataEC50:  853nMAssay Description:Upregulation of Hsp70 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191363(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  311nMAssay Description:Upregulation of Hsp70 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191365(Allyl-((12E,16Z,18E)-(7R,9S,10R,11S,14S,15S)-14-ca...)
Affinity DataEC50:  435nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191363(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  190nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191365(Allyl-((12E,16Z,18E)-(7R,9S,10R,11S,14S,15S)-14-ca...)
Affinity DataEC50:  3.23E+3nMAssay Description:Upregulation of Hsp70 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50030868((8S,9S,12S,13R,14S,16R)-19-amino-13-hydroxy-8,14-d...)
Affinity DataEC50:  17nMAssay Description:Upregulation of Hsp70 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191366(17-((S)-amino-3,2-propanediol)-17-demethoxygeldana...)
Affinity DataEC50:  321nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191364(17-((S)-amino-3,2-propanediol)-17-demethoxygeldana...)
Affinity DataEC50:  140nMAssay Description:Upregulation of Hsp70 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191367(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  27nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataEC50:  22nMAssay Description:Upregulation of Hsp70 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366480(ADENOSINE TRIPHOSPHATE | ATP)
Affinity DataEC50:  1.90E+4nMAssay Description:Inhibition of BODIPY-AG binding to dog Grp94More data for this Ligand-Target Pair
TargetEndoplasmin(Canis familiaris)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191366(17-((S)-amino-3,2-propanediol)-17-demethoxygeldana...)
Affinity DataEC50:  131nMAssay Description:Inhibition of BODIPY-AG binding to dog Grp94More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191367(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  119nMAssay Description:Inhibition of BODIPY-AG binding to dog Grp94More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191368(17-amino-17-demethoxygeldanamycin hydroquinone hyd...)
Affinity DataEC50:  48nMAssay Description:Inhibition of BODIPY-AG binding to dog Grp94More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50030868((8S,9S,12S,13R,14S,16R)-19-amino-13-hydroxy-8,14-d...)
Affinity DataEC50:  53nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataEC50:  35nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191369(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  1.05E+3nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50368125(ADENOSINE DIPHOSPHATE | ADP)
Affinity DataEC50:  2.10E+4nMAssay Description:Inhibition of BODIPY-AG binding to dog Grp94More data for this Ligand-Target Pair
TargetEndoplasmin(Canis familiaris)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191365(Allyl-((12E,16Z,18E)-(7R,9S,10R,11S,14S,15S)-14-ca...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of BODIPY-AG binding to dog Grp94More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191369(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  742nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191368(17-amino-17-demethoxygeldanamycin hydroquinone hyd...)
Affinity DataEC50:  58nMAssay Description:Upregulation of Hsp70 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191364(17-((S)-amino-3,2-propanediol)-17-demethoxygeldana...)
Affinity DataEC50:  141nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataEC50:  19nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataEC50:  124nMAssay Description:Inhibition of BODIPY-AG binding to dog Grp94More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50030868((8S,9S,12S,13R,14S,16R)-19-amino-13-hydroxy-8,14-d...)
Affinity DataEC50:  8nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191367(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  22nMAssay Description:Upregulation of Hsp70 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191367(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  20nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191368(17-amino-17-demethoxygeldanamycin hydroquinone hyd...)
Affinity DataEC50:  10nMAssay Description:Upregulation of Hsp70 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191369(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  384nMAssay Description:Upregulation of Hsp70 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191369(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  2.28E+3nMAssay Description:Upregulation of Hsp70 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50030868((8S,9S,12S,13R,14S,16R)-19-amino-13-hydroxy-8,14-d...)
Affinity DataEC50:  48nMAssay Description:Inhibition of BODIPY-AG binding to dog Grp94More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191365(Allyl-((12E,16Z,18E)-(7R,9S,10R,11S,14S,15S)-14-ca...)
Affinity DataEC50:  585nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191363(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  1.01E+3nMAssay Description:Upregulation of Hsp70 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191366(17-((S)-amino-3,2-propanediol)-17-demethoxygeldana...)
Affinity DataEC50: >1.00E+4nMAssay Description:Upregulation of Hsp70 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191364(17-((S)-amino-3,2-propanediol)-17-demethoxygeldana...)
Affinity DataEC50:  72nMAssay Description:Inhibition of BODIPY-AG binding to dog Grp94More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191366(17-((S)-amino-3,2-propanediol)-17-demethoxygeldana...)
Affinity DataEC50:  102nMAssay Description:Upregulation of Hsp70 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191363(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  415nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50030868((8S,9S,12S,13R,14S,16R)-19-amino-13-hydroxy-8,14-d...)
Affinity DataEC50:  6nMAssay Description:Upregulation of Hsp70 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191368(17-amino-17-demethoxygeldanamycin hydroquinone hyd...)
Affinity DataEC50:  8nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191364(17-((S)-amino-3,2-propanediol)-17-demethoxygeldana...)
Affinity DataEC50:  4.59E+3nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191367(17-allylamino-17-demethoxygeldanamycin hydroquinon...)
Affinity DataEC50:  16nMAssay Description:Upregulation of Hsp70 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191366(17-((S)-amino-3,2-propanediol)-17-demethoxygeldana...)
Affinity DataEC50:  756nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmin(Canis familiaris)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM31996(17-(dimethylaminoethylamino)-17-demethoxygeldanamy...)
Affinity DataEC50:  65nMAssay Description:Inhibition of BODIPY-AG binding to dog Grp94More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191368(17-amino-17-demethoxygeldanamycin hydroquinone hyd...)
Affinity DataEC50:  31nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed