Found 118 with Last Name = 'tanji' and Initial = 'h' 
Affinity DataIC50: 30nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 30nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of ssRNA06-induced NF-kappaB activation measured after 24 hrs by quanti-b...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR4 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of LPS-...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR7 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of imid...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR2 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as inhibition of Pam2CS-induced N...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR9 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of ODN2...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR3 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of poly...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR5 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of flag...More data for this Ligand-Target Pair
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1delta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1G(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1gamma using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1B(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1beta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric ho...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2beta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric ho...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2delta using KKLNRTLSFAEPG peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2gamma using KKLNRTLSFAEPG peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK4 using KKLNRTLSFAEPG peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric hotspo...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2alpha using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type 1(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1alpha using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 4.84E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 6.72E+3nMAssay Description:Inhibition of TLR8 in human CD14-positive monocytes cells in presence of TLR7 stimulusMore data for this Ligand-Target Pair
Affinity DataIC50: 7.46E+3nMAssay Description:Inhibition of TLR8 in human CD14-positive monocytes cells in presence of TLR4 stimulusMore data for this Ligand-Target Pair
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at TLR8 in human PBMC cells assessed as inhibition of compound 1f-induced TNFalpha production incubated for 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at TLR8 in human PBMC cells assessed as inhibition of compound 1f-induced MCP1 production incubated for 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at TLR8 in human PBMC cells assessed as inhibition of compound 1f-induced IL12 p40 production incubated for 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at TLR8 in human PBMC cells assessed as inhibition of compound 1f-induced IFNgamma production incubated for 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at TLR8 in human PBMC cells assessed as inhibition of compound 1f-induced IL-8 production incubated for 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at TLR8 in human PBMC cells assessed as inhibition of compound 1f-induced IL-6 production incubated for 16 hrs by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
