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Found 710 with Last Name = 'tulp' and Initial = 'mt'
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042715(1-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-...)
Affinity DataKi:  0.0750nMAssay Description:The binding affinity of the compound was measured on histamine H1 receptor using [3H]- mepyramine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020178(CHEMBL294633 | CHEMBL555633 | N-[2-(4-Benzofuran-7...)
Affinity DataKi:  0.150nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020178(CHEMBL294633 | CHEMBL555633 | N-[2-(4-Benzofuran-7...)
Affinity DataKi:  0.150nMAssay Description:Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50231569(Cilansetron | KC-9946)
Affinity DataKi:  0.190nMAssay Description:The binding affinity was measured on 5-hydroxytryptamine 3 receptor using [3H]GR-65630 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042718(1-(3,4-Dihydro-5-thia-2a-aza-acenaphthylen-1-yl)-3...)
Affinity DataKi:  0.190nMAssay Description:The binding affinity of the compound was measured on alpha2-adrenergic receptor using [3H]- clonidine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50176019((R)-8-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperaz...)
Affinity DataKi:  0.200nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039829(CHEMBL92242 | Cyclohexanecarboxylic acid [2-(4-ben...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042714(9-(2-Methyl-imidazol-1-ylmethyl)-4,5,8,9-tetrahydr...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039822(1-(2-Cyclohexyl-ethyl)-4-(2,3-dihydro-benzo[1,4]di...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042712(10-(2-Methyl-imidazol-1-ylmethyl)-5,6,9,10-tetrahy...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039822(1-(2-Cyclohexyl-ethyl)-4-(2,3-dihydro-benzo[1,4]di...)
Affinity DataKi:  0.25nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042713(3-(5-Methyl-1H-imidazol-4-yl)-1-(1-methyl-1H-indol...)
Affinity DataKi:  0.280nMAssay Description:The binding affinity of the compound was measured on glycine receptor using [3H]- strychnine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039824(CHEMBL81728 | N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxi...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039824(CHEMBL81728 | N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxi...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50176024(3-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-pipera...)
Affinity DataKi:  0.300nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50056040(CHEMBL107141 | Cyclohexanecarbothioic acid {2-[4-(...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039818(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(4-phenyl-...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042720(3-(5-Methyl-1H-imidazol-4-yl)-1-(4,5,6,7-tetrahydr...)
Affinity DataKi:  0.330nMAssay Description:The binding affinity of the compound was measured on muscarine M1 receptor using [3H]- pirenzepine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039798(1-Benzofuran-7-yl-4-phenethyl-piperazine; hydrochl...)
Affinity DataKi:  0.370nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50176021(3-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-pipera...)
Affinity DataKi:  0.400nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50123075(4-Fluoro-2-{5-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihy...)
Affinity DataKi:  0.400nMAssay Description:In vitro binding affinity for serotonin reuptake sites in rat frontal cortex membranes by [3H]-paroxetine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50176049(3-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-pipera...)
Affinity DataKi:  0.400nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50176035(8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-2-...)
Affinity DataKi:  0.400nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50176044(3-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-pipera...)
Affinity DataKi:  0.400nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50103826(7-[4-(6-Hydroxy-biphenyl-3-ylmethyl)-piperazin-1-y...)
Affinity DataKi:  0.410nMAssay Description:Binding affinity for dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50020174(1-Benzofuran-7-yl-4-[5-(4-fluoro-phenyl)-1H-pyrrol...)
Affinity DataKi:  0.420nMAssay Description:Binding affinity for dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039821(CHEMBL93421 | Cyclohexanecarboxylic acid {2-[4-(2,...)
Affinity DataKi:  0.440nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020174(1-Benzofuran-7-yl-4-[5-(4-fluoro-phenyl)-1H-pyrrol...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039810(1-Benzofuran-7-yl-4-(2-phenoxy-ethyl)-piperazine; ...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039800(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-phenethyl-...)
Affinity DataKi:  0.470nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50103839(7-{4-[4-(4-Fluoro-phenyl)-pyridin-2-ylmethyl]-pipe...)
Affinity DataKi:  0.470nMAssay Description:Binding affinity for dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50176020((R)-8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl...)
Affinity DataKi:  0.5nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039819(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-hexyl-pipe...)
Affinity DataKi:  0.5nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039819(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-hexyl-pipe...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50176042(5-Chloro-3-{3-[4-(2,3-dihydro-benzo[1,4]dioxin-5-y...)
Affinity DataKi:  0.5nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039805(1-Benzofuran-7-yl-4-hexyl-piperazine | CHEMBL27558)
Affinity DataKi:  0.540nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039805(1-Benzofuran-7-yl-4-hexyl-piperazine | CHEMBL27558)
Affinity DataKi:  0.540nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50176034(8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-4H...)
Affinity DataKi:  0.600nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50176045(3-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-pipera...)
Affinity DataKi:  0.600nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50123069(2-(4-(4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridi...)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity for serotonin reuptake sites in rat frontal cortex membranes by [3H]-paroxetine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039796(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-octyl-pipe...)
Affinity DataKi:  0.610nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039796(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-octyl-pipe...)
Affinity DataKi:  0.610nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042711(11-(2-Methyl-imidazol-1-ylmethyl)-4,5,6,7,10,11-he...)
Affinity DataKi:  0.640nMAssay Description:The binding affinity of the compound was measured on dopamine receptor D1 using [3H]- dopamine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042711(11-(2-Methyl-imidazol-1-ylmethyl)-4,5,6,7,10,11-he...)
Affinity DataKi:  0.640nMAssay Description:The binding affinity of the compound was measured on 5-hydroxytryptamine 1C receptor using [3H]- serotonin as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039814(4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...)
Affinity DataKi:  0.670nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50020177(1-(3,4-Dihydro-2H-benzo[b][1,4]dioxepin-6-yl)-4-(5...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Solvay Pharma

Curated by ChEMBL
LigandPNGBDBM50176041((S)-8-{4-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-piper...)
Affinity DataKi:  0.700nMAssay Description:In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50470650(CHEMBL335401)
Affinity DataKi:  0.708nMAssay Description:Inhibition of [3H]2-(di-N-propylamino)-8-hydroxytetralin binding to 5-HT1A receptor of rat frontal cortex homogenatesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Solvay Duphar Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50039807(1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(2-phenoxy...)
Affinity DataKi:  0.730nMAssay Description:Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50042711(11-(2-Methyl-imidazol-1-ylmethyl)-4,5,6,7,10,11-he...)
Affinity DataKi:  0.75nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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