Compile Data Set for Download or QSAR
maximum 50k data
Found 868 with Last Name = 'vomero' and Initial = 's'
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50166996(2-(4-Methyl-piperazin-1-yl)-3-propyl-quinoline-4-c...)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50167002(3-Methyl-2-(4-methyl-piperazin-1-yl)-quinoline-4-c...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity towards Serotonin transporter was determined in rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)
Affinity DataKi:  0.120nMAssay Description:Ability to displace [3H]paroxetine bound to Serotonin transporter receptor in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity of compound was determined against Opioid receptor delta 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027063(CHEMBL2111838)
Affinity DataKi:  0.170nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50167013(4-Methyl-2-(4-methyl-piperazin-1-yl)-quinoline-3-c...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027063(CHEMBL2111838)
Affinity DataKi:  0.170nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027064(CHEMBL2111836)
Affinity DataKi:  0.190nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50167015(3-Ethyl-2-(4-methyl-piperazin-1-yl)-quinoline-4-ca...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50063263(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-ph...)
Affinity DataKi:  0.230nMAssay Description:Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50063263(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-ph...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50063263(6-(4-Methyl-piperazin-1-yl)-7,8,9,10-tetrahydro-ph...)
Affinity DataKi:  0.230nMAssay Description:Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50167011(4-(4-Methyl-piperazin-1-yl)-2,3-dihydro-1H-cyclope...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.240nMAssay Description:Binding affinity determined against Opioid receptor delta 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131967(CHEMBL123898 | N-[2-(5-Phenyl-2,3-dihydro-1H-benzo...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131967(CHEMBL123898 | N-[2-(5-Phenyl-2,3-dihydro-1H-benzo...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131972(4-Fluoro-N-[2-(5-phenyl-2,3-dihydro-1H-benzo[e][1,...)
Affinity DataKi:  0.280nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131972(4-Fluoro-N-[2-(5-phenyl-2,3-dihydro-1H-benzo[e][1,...)
Affinity DataKi:  0.280nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049802(4-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049802(4-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50449636(BRL-43694 | GRANISETRON | Kytril | LY-278584 | San...)
Affinity DataKi:  0.350nMAssay Description:Ability to displace [3H]granisetron specifically bound to 5-hydroxytryptamine 3 receptor in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049807(2-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049807(2-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50167014(3-Methyl-2-(4-methyl-piperazin-1-yl)-quinoline-4-c...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131968(CHEMBL127828 | Thiophene-3-carboxylic acid {2-[5-(...)
Affinity DataKi:  0.370nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50076415(2-[2-(4-Methyl-piperazin-1-yl)-4-phenyl-quinolin-3...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50167004(2-(4-Methyl-piperazin-1-yl)-quinoline-4-carboxylic...)
Affinity DataKi:  0.410nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50167003(3-Methyl-2-(4-methyl-piperazin-1-yl)-quinoline-4-c...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027064(CHEMBL2111836)
Affinity DataKi:  0.430nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50027064(CHEMBL2111836)
Affinity DataKi:  0.430nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50166997(3-Methyl-2-(4-methyl-piperazin-1-yl)-quinoline-4-c...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131969(CHEMBL126688 | Thiophene-2-carboxylic acid [2-(5-p...)
Affinity DataKi:  0.450nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131969(CHEMBL126688 | Thiophene-2-carboxylic acid [2-(5-p...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131973(CHEMBL338391 | N-[2-(1-Methyl-5-phenyl-2,3-dihydro...)
Affinity DataKi:  0.470nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131973(CHEMBL338391 | N-[2-(1-Methyl-5-phenyl-2,3-dihydro...)
Affinity DataKi:  0.480nMAssay Description:Binding constant towards human Opioid receptor kappa 1 was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049806(CHEMBL127969 | Thiophene-2-carboxylic acid [2-(1-m...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity against Opioid receptor kappa 1 of guinea pig using [3H]-U-65,693 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049806(CHEMBL127969 | Thiophene-2-carboxylic acid [2-(1-m...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049806(CHEMBL127969 | Thiophene-2-carboxylic acid [2-(1-m...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50167016(3-Ethyl-2-(4-methyl-piperazin-1-yl)-quinoline-4-ca...)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131970(2-Fluoro-N-[2-(5-phenyl-2,3-dihydro-1H-benzo[e][1,...)
Affinity DataKi:  0.530nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131970(2-Fluoro-N-[2-(5-phenyl-2,3-dihydro-1H-benzo[e][1,...)
Affinity DataKi:  0.530nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50167005(3-Methyl-2-(4-methyl-piperazin-1-yl)-quinoline-4-c...)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049808(CHEMBL127968 | N-[2-(7-Chloro-1-methyl-5-phenyl-2,...)
Affinity DataKi:  0.550nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049802(4-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  0.560nMAssay Description:Binding affinity against Opioid receptor kappa 1 of guinea pig using [3H]-U-65,693 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50049802(4-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-be...)
Affinity DataKi:  0.560nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50166991(3-Methyl-2-piperazin-1-yl-quinoline-4-carboxylic a...)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50076416(2-[4-(2-Fluoro-phenyl)-2-(4-methyl-piperazin-1-yl)...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50076401(CHEMBL41511 | [2-(4-Methyl-piperazin-1-yl)-4-pheny...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50167000(2-(4-Methyl-piperazin-1-yl)-quinoline-4-carboxylic...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]granisetron from 5-hydroxytryptamine 3 receptor of rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 868 total ) | Next | Last >>
Jump to: